Michael Breindl

University of North Carolina at Chapel Hill — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index2.3kcitations49works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Virus-based gene therapy research(11), Cancer-related gene regulation(9), Cell Adhesion Molecules Research(8), Genomics and Chromatin Dynamics(7), RNA Research and Splicing(7)

Publications49 total

Binding of Upstream Stimulatory Factor to an E-box in the 3′-Flanking Region Stimulates α1(I) Collagen Gene Transcription
UNC Libraries·2021Open Access
DNase I-hypersensitive sites enhance α1(I) collagen gene expression in hepatic stellate cells
Hepatology·2003· 201 citedOpen Access
Multiple collagen I gene regulatory elements have sites of stress‐induced DNA duplex destabilization and nuclear scaffold/matrix association potential
Journal of Cellular Biochemistry·2002· 7 cited
Multiple collagen I gene regulatory elements have sites of stress-induced DNA duplex destabilization and nuclear scaffold/matrix association potential
Journal of Cellular Biochemistry·2002· 1 cited
Collagen promoter-GFP transgenic mice provide a model to study collagen gene expression during experimental intestinal inflammation and injury in vivo and in vitro
Gastroenterology·2001
Far upstream regulatory elements enhance position-independent and uterus-specific expression of the murine alpha1(I) collagen promoter in transgenic mice.
PubMed·1999· 62 citedOpen Access
Molecular cloning and chromatin structure analysis of the murine α1(I) collagen gene domain
Gene·1997· 10 cited
Binding of Upstream Stimulatory Factor to an E-box in the 3′-Flanking Region Stimulates α1(I) Collagen Gene Transcription
Journal of Biological Chemistry·1997· 44 citedOpen Access
Correct cell- and differentiation-specific expression of a murine alpha 1 (I) collagen minigene in vitro differentiating embryonal carcinoma cells.
PubMed·1996· 5 cited
Fibrogenesis and type I collagen gene regulation.
PubMed·1994· 40 cited
DNA Methylation Represses the Murine αl (I) Collagen Promoter by an Indirect Mechanism
Molecular and Cellular Biology·1994· 9 cited
DNA methylation represses the murine alpha 1(I) collagen promoter by an indirect mechanism.
Molecular and Cellular Biology·1994· 45 citedOpen Access
Type I collagen gene regulation and the molecular pathogenesis of cirrhosis
American Journal of Physiology-Gastrointestinal and Liver Physiology·1993· 32 cited
Developmental changes in the methylation status of regulatory elements in the murine alpha 1(I) collagen gene.
PubMed·1992· 16 citedOpen Access
Retrovirus-Induced Insertional Mutagenesis: Mechanism of Collagen Mutation in Mov13 Mice
Molecular and Cellular Biology·1991· 23 cited
Retrovirus-Induced Interference with Collagen I Gene Expression in Movl3 Fibroblasts Is Maintained in the Absence of DNA Methylation
Molecular and Cellular Biology·1991· 8 cited
Retrovirus-induced interference with collagen I gene expression in Mov13 fibroblasts is maintained in the absence of DNA methylation.
Molecular and Cellular Biology·1991· 18 citedOpen Access
Elevated expression of v-mos is correlated with altered differentiation of carcinoma cells.
PubMed·1990· 3 cited
Transcriptionally active genome regions are preferred targets for retrovirus integration
Journal of Virology·1990· 212 citedOpen Access
Regulatory Elements in the 5′-Flanking Region and the First Intron Contribute to Transcriptional Control of the Mouse Alpha 1 Type I Collagen Gene
Molecular and Cellular Biology·1989· 40 cited
page 1 of 3Next →

Frequent Co-authors

David A. Brenner(11), Rudolf Jaenisch(10), Richard A. Rippe(10), Katherine Rhodes(6), John J. Holland(5), Stefan Hartung(4), Akihiro Umezawa(4), U Scherdin(3), Luis P. Villarreal(3), Klaus Harbers(3), Dieter Gallwitz(3), Hans Weiher(2), Wolf Reik(2), Andrea Gillan(2), Sven-Iver Lorenzen(2), K. Hall(2), Michael Nehls(2), Jon P. Kimball(2), Johannes Doehmer(2), Klaus Willecke(2)