Patricia M. Rosten

BC Cancer Agency — Canada

Medicine · Health Sciences

14h-index1.7kcitations24works0.02yr avg
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Research Topics

Acute Myeloid Leukemia Research(6), CRISPR and Genetic Engineering(5), Virus-based gene therapy research(3), Protein Degradation and Inhibitors(3), Protein Kinase Regulation and GTPase Signaling(2)

Publications24 total

A knock-in mouse strain facilitates dynamic tracking and enrichment of MEIS1
Blood Advances·2017· 9 citedOpen Access
Meis2 as a critical player in MN1-induced leukemia
Blood Cancer Journal·2017· 20 citedOpen Access
A Lentiviral Fluorescent Genetic Barcoding System for Flow Cytometry-Based Multiplex Tracking
Molecular Therapy·2017· 18 citedOpen Access
Discovery of MEIS2 as a critical player in leukemogenesis using an MN1-leukemia model
Experimental Hematology·2016
Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13
Blood·2014· 26 citedOpen Access
Delineating key MEIS1 cis-regulatory elements through CRISPR/Cas9 mediated targeting
Experimental Hematology·2014
Delineating MEIS1 cis-regulatory elements active in hematopoietic cells
Leukemia·2013· 8 cited
The role of toxic shock syndrome toxin-1 in the pathogenesis of toxic shock syndrome
Open Collections·2010Open Access
Therapeutic Effect of HOXB4-Expanded Stem Cells in Mice with Beta Thalassemia Given a Non-Myeloablative Conditioning Regimen.
Blood·2006
The AML1-ETO Fusion Gene and the FLT3 Length Mutation Collaborate in Inducing Acute Leukemia in a Murine Bone Marrow Transplantation Model.
Blood·2005
The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice
Journal of Clinical Investigation·2005· 240 citedOpen Access
Redundant Leukemogenicity of NUP98-HOX Fusion Genes in Primary Murine Bone Marrow Cells Correlates with Gene Expression Changes Consistent with Common Key Target Genes.
Blood·2004
High-level β-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells
Journal of Clinical Investigation·2004· 102 citedOpen Access
High-level β-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells
Journal of Clinical Investigation·2004· 113 cited
Overexpression of HOXA10 perturbs human lymphomyelopoiesis in vitro and in vivo
Blood·2001· 111 cited
HOXA10-Overexpression causes severe perturbations in human hematopoiesis
Experimental Hematology·2000· 1 cited
The role of erythropoietin receptor tyrosine phosphorylation in erythropoietin-induced proliferation.
PubMed·1997· 18 cited
Cloning and characterization of human SHIP, the 145-kD inositol 5- phosphatase that associates with SHC after cytokine stimulation
Blood·1996· 100 cited
The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase.
Proceedings of the National Academy of Sciences·1996· 635 citedOpen Access
Mapping of CD24 and Homologous Sequences to Multiple Chromosomal Loci
Genomics·1994· 62 cited
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Frequent Co-authors

R. Keith Humphries(19), Connie J. Eaves(6), Michaela Feuring‐Buske(4), Christian Buske(4), Suzan Imren(4), Gudmundur L. Norddahl(4), Tobias Maetzig(4), Gerald Krystal(3), Anthony W. Chow(3), Ping Xiang(3), Niklas von Krosigk(3), Pamela A. Hoodless(3), Christina Schessl(2), Vijay P.S. Rawat(2), Monica Cusan(2), Aniruddha J. Deshpande(2), Tobias Kohl(2), Karsten Spiekermann(2), Susanne Schnittger(2), Wolfgang Kern(2)