Sharon J. Schultz

University of Washington — United States

Immunology and Microbiology · Life Sciences

12h-index914citations14works0.02yr avg

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Research Topics

HIV Research and Treatment(11), HIV/AIDS drug development and treatment(11), Cytomegalovirus and herpesvirus research(3), DNA and Nucleic Acid Chemistry(2), Microtubule and mitosis dynamics(2)

Publications14 total

Multiple Nucleotide Preferences Determine Cleavage-Site Recognition by the HIV-1 and M-MuLV RNases H

11 cited

Journal of Molecular Biology·2010· 11 citedOpen Access

Preferred Sequences within a Defined Cleavage Window Specify DNA 3′ End-directed Cleavages by Retroviral RNases H

13 cited

Journal of Biological Chemistry·2009· 13 citedOpen Access

Ribonuclease H: properties, substrate specificity and roles in retroviral reverse transcription

74 cited

FEBS Journal·2009· 74 citedOpen Access

RNase H activity: Structure, specificity, and function in reverse transcription

145 cited

Virus Research·2008· 145 citedOpen Access

Substitution of alanine for tyrosine-64 in the fingers subdomain of M-MuLV reverse transcriptase impairs strand displacement synthesis and blocks viral replication in vivo

11 cited

Virology·2007· 11 citedOpen Access

Sequence, Distance, and Accessibility Are Determinants of 5′-End-directed Cleavages by Retroviral RNases H

35 cited

Journal of Biological Chemistry·2005· 35 citedOpen Access

Recognition of Internal Cleavage Sites by Retroviral RNases H

35 cited

Journal of Molecular Biology·2004· 35 cited

DNA relaxation by human topoisomerase I occurs in the closed clamp conformation of the protein

43 cited

Proceedings of the National Academy of Sciences·2003· 43 citedOpen Access

Specific Cleavages by RNase H Facilitate Initiation of Plus-Strand RNA Synthesis by Moloney Murine Leukemia Virus

20 cited

Journal of Virology·2003· 20 citedOpen Access

Analysis of Plus-strand Primer Selection, Removal, and Reutilization by Retroviral Reverse Transcriptases

31 cited

Journal of Biological Chemistry·2000· 31 citedOpen Access

Polypurine Tract Primer Generation and Utilization by Moloney Murine Leukemia Virus Reverse Transcriptase

31 cited

Journal of Biological Chemistry·1999· 31 citedOpen Access

Cleavage Specificities of Moloney Murine Leukemia Virus RNase H Implicated in the Second Strand Transfer During Reverse Transcription

24 cited

Journal of Biological Chemistry·1995· 24 citedOpen Access

Substrate Specificity and Cell Cycle Regulation of the Nek2 Protein Kinase, a Potential Human Homolog of the Mitotic Regulator NIMA of Aspergillus nidulans

161 cited

Journal of Biological Chemistry·1995· 161 citedOpen Access

Cell cycle analysis and chromosomal localization of human Plk1, a putative homologue of the mitotic kinases <i>Drosophila</i> polo and <i>Saccharomyces cerevisiae</i> Cdc5

280 cited

Journal of Cell Science·1994· 280 cited

Frequent Co-authors

James J. Champoux(12), Miaohua Zhang(8), Jiří Bártek(2), Erich A. Nigg(2), Colleen D. Kelleher(2), Roy M. Golsteyn(1), Andrew Ziemiecki(1), Thomas Ried(1), Andrew M. Fry(1), James F. Carey(1), Lisa Sisson(1), Thomas G. Fazzio(1), Samuel H. Whiting(1), Benjamin A. Paulson(1)