Kiyoshi Isono

Medicine · Health Sciences

39h-index5.0kcitations195works0.02yr avg
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Research Topics

Microbial Natural Products and Biosynthesis(59), Carbohydrate Chemistry and Synthesis(38), Cancer therapeutics and mechanisms(33), Chemical Synthesis and Analysis(31), Bioactive Compounds and Antitumor Agents(24)

Publications195 total

N-Acetylglycine Side Chain is Critical for the Antimicrobial Activity of Xanthostatin
Journal of Microbiology and Biotechnology·2003· 6 cited
New Types of Liposidomycins that Inhibit Bacterial Peptidoglycan Synthesis and are Produced by Streptomyces. I. Producing Organism and Medium Components.
The Journal of Antibiotics·1998· 36 citedOpen Access
New Types of Liposidomycins Which Inhibit Bacterial Peptidoglycan Synthesis Produced by Streptomyces.
Actinomycetologica·1998· 3 citedOpen Access
Selective Inhibition of the Bacterial Peptidoglycan Biosynthesis by the New Types of Liposidomycins.
The Journal of Antibiotics·1998· 69 citedOpen Access
New Types of Liposidomycins that Inhibit Bacterial Peptidoglycan Synthesis and are Produced by Streptomyces. II. Isolation and Structure Elucidation.
The Journal of Antibiotics·1998· 40 citedOpen Access
Synthetic studies on tautomycin synthesis of Segment B
Tetrahedron·1997· 24 cited
A Pharmacophore Model of Tautomycin, an Inhibitor of Protein Phosphatases 1 and 2A.
The Journal of Antibiotics·1997· 8 citedOpen Access
Structure-Activity Relationship within a Series of Degradation Products of Tautomycin
Bioscience Biotechnology and Biochemistry·1996· 12 citedOpen Access
Acetophthalidin, a Novel Inhibitor of Mammalian Cell Cycle, Produced by a Fungus Isolated from a Sea Sediment.
The Journal of Antibiotics·1996· 43 citedOpen Access
Molecular shape analysis and activity of tautomycin, a protein phosphatase inhibitor
Bioorganic & Medicinal Chemistry Letters·1996· 35 cited
Tautomycin: An inhibitor of protein phosphatases 1 and 2A but not a tumor promoter on mouse skin and in rat glandular stomach
Journal of Cancer Research and Clinical Oncology·1995· 19 citedOpen Access
Liposidolide A, a New Antifungal Macrolide Antibiotic.
The Journal of Antibiotics·1995· 19 citedOpen Access
A New Cyclic Lipopeptide Antibiotic, Enamidonin.
The Journal of Antibiotics·1995· 22 citedOpen Access
Epolactaene, a Novel Neuritogenic Compound in Human Neuroblastoma Cells, Produced by a Marine Fungus.
The Journal of Antibiotics·1995· 141 citedOpen Access
RS-22A, B and C: New Macrolide Antibiotics from Streptomyces violaceusniger. I. Taxonomy, Fermentation, Isolation and Biological Activities.
The Journal of Antibiotics·1995· 29 citedOpen Access
Biosynthesis of the dialkylmaleic anhydride-containing antibiotics, tautomycin and tautomycetin
Journal of the Chemical Society Perkin Transactions 1·1995· 21 cited
Tryprostatins A and B, Novel Mammalian Cell Cycle Inhibitors Produced by Aspergdlus fumigatus .
The Journal of Antibiotics·1995· 137 citedOpen Access
Efficient Degradation of Tautomycin to a Useful Synthetic Intermediate
Bioscience Biotechnology and Biochemistry·1994· 6 cited
Absolute configuration of reveromycin A, an inhibitor of the signal transduction of epidermal growth factor
Journal of the Chemical Society Chemical Communications·1994· 21 cited
Structural identity and stereochemical revision of polyoximic acid
Tetrahedron Letters·1993· 24 cited
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Frequent Co-authors

Hiroyuki Osada(18), Makoto Ubukata(12), Masakazu Uramoto(10), James A. McCloskey(9), Hiroo Kusakabe(8), Saburo Suzuki(7), Kimie Kobinata(7), Hiroyuki Koshino(7), Xing-Chun Cheng(6), Ken‐ichi Kimura(5), Makoto Yoshihama(5), Rie Onose(4), Junsaku Nagatsu(4), Hidetoshi Takahashi(4), Hideaki Kakeya(3), Isamu Takahashi(3), Gen Okada(3), Chad Nelson(3), Junji Magae(3), Hidetoshi Takahashi(3)