Lasse Tengbjerg Hansen

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index2.0kcitations21works0.02yr avg
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Research Topics

DNA Repair Mechanisms(5), Immunotherapy and Immune Responses(5), Immune Cell Function and Interaction(5), Cancer therapeutics and mechanisms(5), Virus-based gene therapy research(4)

Publications21 total

Data from Clinical and Biological Efficacy of Recombinant Human Interleukin-21 in Patients with Stage IV Malignant Melanoma without Prior Treatment: A Phase IIa Trial
2023Open Access
Data from Clinical and Biological Efficacy of Recombinant Human Interleukin-21 in Patients with Stage IV Malignant Melanoma without Prior Treatment: A Phase IIa Trial
2023Open Access
Supplementary Figures S1-S3 from Clinical and Biological Efficacy of Recombinant Human Interleukin-21 in Patients with Stage IV Malignant Melanoma without Prior Treatment: A Phase IIa Trial
2023Open Access
Supplementary Figures S1-S3 from Clinical and Biological Efficacy of Recombinant Human Interleukin-21 in Patients with Stage IV Malignant Melanoma without Prior Treatment: A Phase IIa Trial
2023Open Access
Multivariate evaluation of pharmacological responses in early clinical trials – a study of rIL‐21 in the treatment of patients with metastatic melanoma
British Journal of Clinical Pharmacology·2009· 17 citedOpen Access
Clinical and Biological Efficacy of Recombinant Human Interleukin-21 in Patients with Stage IV Malignant Melanoma without Prior Treatment: A Phase IIa Trial
Clinical Cancer Research·2009· 138 cited
Immune activation in advanced cancer patients treated with recombinant IL-21: multianalyte profiling of serum proteins
Cancer Immunology Immunotherapy·2008· 21 citedOpen Access
Thymidine Selectively Enhances Growth Suppressive Effects of Camptothecin/Irinotecan in MSI+ Cells and Tumors Containing a Mutation of <i>MRE11</i>
Clinical Cancer Research·2008· 39 cited
IL-21 induces in vivo immune activation of NK cells and CD8+ T cells in patients with metastatic melanoma and renal cell carcinoma
Cancer Immunology Immunotherapy·2008· 114 citedOpen Access
OR.85. Leukocyte Responses during Recombinant Human Interleukin-21 Treatment of Patients with Stage IV Melanoma
Clinical Immunology·2008
Combined Pharmacodynamic and Transcriptome Profiling of Recombinant Human Interleukin-21 Responses in Patients with Stage IV Malignant Melanoma
Clinical Immunology·2007
Augmenting tumor sensitivity to topotecan by transient hypoxia
Cancer Chemotherapy and Pharmacology·2005· 8 cited
Inhibition of Human Chk1 Causes Increased Initiation of DNA Replication, Phosphorylation of ATR Targets, and DNA Breakage
Molecular and Cellular Biology·2005· 548 citedOpen Access
Regulation of YKL‐40 expression during genotoxic or microenvironmental stress in human glioblastoma cells
Cancer Science·2005· 125 citedOpen Access
The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair
Nature Cell Biology·2005· 646 cited
Characterisation of cytotoxicity and DNA damage induced by the topoisomerase II-directed bisdioxopiperazine anti-cancer agent ICRF-187 (dexrazoxane) in yeast and mammalian cells
BMC Pharmacology·2004· 19 citedOpen Access
Differential regulation of VEGF, HIF1α and angiopoietin‐1, ‐2 and ‐4 by hypoxia and ionizing radiation in human glioblastoma
International Journal of Cancer·2004· 68 citedOpen Access
P-128 Regulation of RAD51 levels in response to etoposide (VP16) induced DNA strand breaks in small cell lung cancer cells
Lung Cancer·2003
DNA repair rate and etoposide (VP16) resistance of tumor cell subpopulations derived from a single human small cell lung cancer
Lung Cancer·2003· 34 cited
RAD51 is Involved in Repair of Damage Associated with DNA Replication in Mammalian Cells
Journal of Molecular Biology·2003· 113 cited
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Frequent Co-authors

Kresten Skak(9), Dorthe Lundsgaard(9), Klaus Stensgaard Frederiksen(9), Ian D. Davis(8), Birte K. Skrumsager(8), Paul E.G. Kristjansen(8), Grant A. McArthur(8), Ulrik Mouritzen(7), Thomas Helleday(6), Michael Millward(5), Jonathan Cebon(5), Cecilia Lundin(4), Ben Brady(4), Richard F. Kefford(4), Claus Storgaard Sørensen(3), Eva Løbner Lund(3), Mogens Spang‐Thomsen(3), Randi G. Syljuåsen(2), Jiří Bártek(2), Maxwell Sehested(2)