M Kuppuswamy

Saint Louis University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index1.8kcitations30works0.02yr avg
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Research Topics

Virus-based gene therapy research(16), Blood Coagulation and Thrombosis Mechanisms(8), Viral Infectious Diseases and Gene Expression in Insects(8), CAR-T cell therapy research(7), RNA Interference and Gene Delivery(4)

Publications30 total

Interaction of cellular proteins with BCL-xL targeted to cytoplasmic inclusion bodies in adenovirus infected cells
Virology·2015· 8 citedOpen Access
Evaluation of apoptogenic adenovirus type 5 oncolytic vectors in a Syrian hamster head and neck cancer model
Cancer Gene Therapy·2014· 8 citedOpen Access
A fully replication-competent adenovirus vector with enhanced oncolytic properties
Cancer Gene Therapy·2010· 10 cited
Interaction of ZEB and Histone Deacetylase with the PLDLS-binding cleft region of monomeric C-terminal Binding Protein 2
BMC Molecular Biology·2009· 48 citedOpen Access
INGN 007, an oncolytic adenovirus vector, replicates in Syrian hamsters but not mice: comparison of biodistribution studies
Cancer Gene Therapy·2009· 59 cited
An acute toxicology study with INGN 007, an oncolytic adenovirus vector, in mice and permissive Syrian hamsters; comparisons with wild-type Ad5 and a replication-defective adenovirus vector
Cancer Gene Therapy·2009· 51 cited
Anticancer activity of oncolytic adenovirus vector armed with IFN-α and ADP is enhanced by pharmacologically controlled expression of TRAIL
Cancer Gene Therapy·2007· 46 cited
Role of the PLDLS-Binding Cleft Region of CtBP1 in Recruitment of Core and Auxiliary Components of the Corepressor Complex
Molecular and Cellular Biology·2007· 164 citedOpen Access
2349
International Journal of Radiation Oncology*Biology*Physics·2006Open Access
Oncolytic adenovirus that overproduces ADP and replicates selectively in tumors due to hTERT promoter-regulated E4 gene expression
Gene Therapy·2005· 39 cited
Synergistic effects of specially designed replication competent adenovirus vector and radiotherapy
International Journal of Radiation Oncology*Biology*Physics·2000
Synthesis and Expression of Tissue Factor Pathway Inhibitor by Serum-stimulated Fibroblasts, Vascular Smooth Muscle Cells and Cardiac Myocytes
Thrombosis and Haemostasis·1999· 31 cited
2035 Replication competent adnovirus anticancer vectors — Radiotherapy synergy experiment in tissue culture phase
International Journal of Radiation Oncology*Biology*Physics·1999
Transcriptional Expression of Tissue Factor Pathway Inhibitor, Thrombomodulin and von Willebrand Factor in Normal Human Tissues
Thrombosis and Haemostasis·1999· 80 cited
Revised cDNA sequence of rabbit tissue factor pathway inhibitor
Thrombosis Research·1993· 9 cited
Expression of tissue factor pathway inhibitor by cultured endothelial cells in response to inflammatory mediators
Blood·1992· 109 citedOpen Access
Expression of tissue factor pathway inhibitor by cultured endothelial cells in response to inflammatory mediators
Blood·1992· 89 citedOpen Access
Single nucleotide primer extension to detect genetic diseases: experimental application to hemophilia B (factor IX) and cystic fibrosis genes.
Proceedings of the National Academy of Sciences·1991· 171 citedOpen Access
Cultured normal human hepatocytes do not synthesize lipoprotein-associated coagulation inhibitor: evidence that endothelium is the principal site of its synthesis.
Proceedings of the National Academy of Sciences·1990· 264 citedOpen Access
Factor IXHollywood: substitution of Pro55 by Ala in the first epidermal growth factor-like domain
Blood·1990· 18 citedOpen Access
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Frequent Co-authors

G. Chinnadurai(13), T. Subramanian(10), William S.M. Wold(7), Károly Tóth(6), Konstantin Doronin(6), S Paul Bajaj(5), S. Vijayalingam(4), Jacqueline F. Spencer(4), Ann E. Tollefson(4), Elena V. Shashkova(4), Megha Bajaj(3), SP Bajaj(3), S G Spitzer(2), Ashish Srinivasan(2), Ling‐Jun Zhao(2), Afshin Ameri(2), Sunanda Basu(2), S Mak(2), Jenifer Meyer(2), Debabrata Patra(2)