H. Bobby Gaspar

Great Ormond Street Hospital — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index3.0kcitations44works10.52yr avg
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Research Topics

Virus-based gene therapy research(19), Immunodeficiency and Autoimmune Disorders(17), CAR-T cell therapy research(14), Cytomegalovirus and herpesvirus research(7), RNA Interference and Gene Delivery(6)

Publications41 total

Long-Term Safety and Efficacy of Gene Therapy for Adenosine Deaminase Deficiency
New England Journal of Medicine·2025· 5 cited
Development of Anti-CD45 Antibody Drug Conjugates As Targeted Conditioning Agents for Transplantation/Gene Therapy with Potent Anti-Leukemic Properties
Blood·2022
Author Correction: Metabolite and thymocyte development defects in ADA-SCID mice receiving enzyme replacement therapy
Scientific Reports·2021· 1 citedOpen Access
Gene therapy for adenosine deaminase deficiency
Gene Therapy·2020
Consensus approach for the management of severe combined immune deficiency caused by adenosine deaminase deficiency
Journal of Allergy and Clinical Immunology·2018· 128 cited
How We Manage Adenosine Deaminase-Deficient Severe Combined Immune Deficiency (ADA SCID)
Journal of Clinical Immunology·2017· 45 cited
A prospective study on the natural history of patients with profound combined immunodeficiency: An interim analysis
Journal of Allergy and Clinical Immunology·2016· 61 citedOpen Access
250. A Phase 2/3 Study of the Efficacy and Safety of Ex Vivo Gene Therapy with Lenti-D TM Lentiviral Vector for the Treatment of Cerebral Adrenoleukodystrophy
Molecular Therapy·2016· 2 citedOpen Access
Hematopoietic stem cell transplantation outcomes for 11 patients with dedicator of cytokinesis 8 deficiency
Journal of Allergy and Clinical Immunology·2016· 56 citedOpen Access
A novel Rab27a mutation binds melanophilin, but not Munc13-4, causing immunodeficiency without albinism
Journal of Allergy and Clinical Immunology·2016· 28 citedOpen Access
Combined immunodeficiency due to JAK3 mutation in a child presenting with skin granuloma
Journal of Allergy and Clinical Immunology·2015· 7 citedOpen Access
Chronic Infection with Rotavirus Vaccine Strains in UK Children with Severe Combined Immunodeficiency
The Pediatric Infectious Disease Journal·2015· 23 cited
DOCK8 Deficiency: Clinical and Immunological Phenotype and Treatment Options - a Review of 136 Patients
Journal of Clinical Immunology·2015· 306 citedOpen Access
Gene Therapy as a Future Management Option for Hemophagocytic Lymphohistiocytosis
The Journal of OncoPathology·2014
Hematopoietic SCT in Europe: data and trends in 2012 with special consideration of pediatric transplantation
Bone Marrow Transplantation·2014· 173 citedOpen Access
X-SCID paper 2011
2014
Preimplantation Genetic Diagnosis and HLA-Typing: The Potential for Selection of Unaffected HLA Matched Siblings
2013· 1 cited
Gene Therapy for Primary Immunodeficiency
Encyclopedia of Life Sciences·2013· 13 cited
Hematopoietic SCT in Europe: data and trends in 2011
Bone Marrow Transplantation·2013· 131 citedOpen Access
SAP gene transfer restores cellular and humoral immune function in a murine model of X-linked lymphoproliferative disease
Blood·2012· 61 citedOpen Access
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Frequent Co-authors

Adrian J. Thrasher(15), Alessandro Aiuti(7), Luigi D. Notarangelo(7), Claire Booth(7), Andrew R. Gennery(6), Kimberly Gilmour(6), Steven J. Howe(5), Donald B. Kohn(5), Waleed Al–Herz(4), Alain Fischer(4), Marina Cavazzana(4), Jakob Passweg(3), Christina Peters(3), Anna Sureda(3), Andrea Velardi(3), Sevgi Keleş(3), Sung‐Yun Pai(3), Talal A. Chatila(3), Paul Veys(3), Caterina Cancrini(3)