Ajay Purohit

Indian Institute of Integrative Medicine — India

Medicine · Health Sciences

14h-index794citations31works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Cardiac Imaging and Diagnostics(6), Medical Imaging Techniques and Applications(6), Estrogen and related hormone effects(6), Cyclization and Aryne Chemistry(6), Advanced MRI Techniques and Applications(5)

Publications31 total

Unveiling the anti-inflammatory wound healing potential of Ocimum canum extract and its phytochemicals via bioassay-guided isolation, fractionation, and computational studies
Scientific Reports·2025Open Access
Anti‐Inflammatory Activity of Novel Dehydrozingerone‐6 (DHZ‐6) Through Modulation of iNOS, COX‐2, and NF‐κB/p65 in LPS‐Stimulated Macrophages and In Vivo Acute Lung Injury Murine Model
Journal of Applied Toxicology·2025
Test–retest characteristic of [<sup>18</sup>F]MK-6240 quantitative outcomes in cognitively normal adults and subjects with Alzheimer’s disease
Journal of Cerebral Blood Flow & Metabolism·2019· 35 citedOpen Access
IC‐P‐176: LONGITUDINAL ASSESSMENT OF TAU WITH [<sup>18</sup>F]MK‐6240 IN ALZHEIMER'S DISEASE PATIENTS AND COGNITIVELY NORMAL ADULTS AT 6 AND 12 MONTHS
Alzheimer s & Dementia·2019Open Access
DT‐02‐06: NOVEL ALPHA‐SYNUCLEIN POSITRON EMISSION TOMOGRAPHY (PET) TRACERS FOR THE DIAGNOSIS OF PARKINSON'S DISEASE
Alzheimer s & Dementia·2018
Synthesis and Cardiac Imaging of<sup>18</sup>F-Ligands Selective for β<sub>1</sub>-Adrenoreceptors
ACS Medicinal Chemistry Letters·2011· 9 citedOpen Access
Evaluation of LMI1195, a Novel <sup>18</sup> F-Labeled Cardiac Neuronal PET Imaging Agent, in Cells and Animal Models
Circulation Cardiovascular Imaging·2011· 108 citedOpen Access
LMI1195: A NEW 18F BENZYLGUANIDINE ANALOG FOR PET CARDIAC SYMPATHETIC NEURONAL IMAGING
Journal of the American College of Cardiology·2010· 2 cited
STX2171, a 17 beta-Hydroxysteroid Dehydrogenase Type 3 (17 beta-HSD3) Inhibitor, Is Efficacious In Vivo in a Novel Hormone-Dependent Prostate Cancer Model.
Endocrine Reviews·2010
Assessment of 18F-labeled mitochondrial complex I inhibitors as PET myocardial perfusion imaging agents in rats, rabbits, and primates
European Journal of Nuclear Medicine and Molecular Imaging·2008· 36 cited
Synthesis and Biological Evaluation of Pyridazinone Analogues as Potential Cardiac Positron Emission Tomography Tracers
Journal of Medicinal Chemistry·2008· 44 cited
BMS-747158-02: A novel PET myocardial perfusion imaging agent
Journal of Nuclear Cardiology·2007· 151 cited
Mechanism of uptake and retention of F-18 BMS-747158-02 in cardiomyocytes: A novel PET myocardial imaging agent
Journal of Nuclear Cardiology·2007· 158 cited
Quinazoline derivatives as MC-I inhibitors: Evaluation of myocardial uptake using Positron Emission Tomography in rat and non-human primate
Bioorganic & Medicinal Chemistry Letters·2007· 16 cited
Nuclear estrogen receptor targeted photodynamic therapy: Selective uptake and killing of MCF‐7 breast cancer cells by a C<sub>17α</sub>‐alkynylestradiol‐porphyrin conjugate
Journal of Cellular Biochemistry·2006· 27 cited
Inhibition of prostate xenograft growth by two novel orally bioavailable microtubule disruptors
European Journal of Cancer Supplements·2006
Sulphamoylated derivatives of 2-methoxyestradiol induce apoptosis in breast, ovarian and prostate cancer cell lines through mitotic arrest via the intrinsic apoptotic pathway
Cancer Research·2006· 1 cited
2-Methoxyestradiol-3,17-O,O-bis-sulfamate binds to the colchicine site of tubulin and down-regulates survivin, inhibits the anti-apoptotic protein Bcl-2 and down-regulates the pro-angiogenic transcription factor HIF-1 alpha
Cancer Research·2006
Synthesis and Protein Degradation Capacity of Photoactivated Enediynes
The Journal of Organic Chemistry·2005· 50 cited
Pyridine-Containing 6-Hydrazinonicotinamide Derivatives as Potential Bifunctional Chelators for <sup>99m</sup>Tc-Labeling of Small Biomolecules
Bioconjugate Chemistry·2004· 16 cited
page 1 of 2Next →

Frequent Co-authors

Mikhail Kagan(8), Michael Azure(8), David S. Casebier(8), Ming Yu(7), Heike Radeke(7), Mary Guaraldi(7), Graham B. Jones(7), Justin M. Wright(6), George W. Hynd(6), Mathew P. Leese(6), Padmaja Yalamanchili(5), Megan Hayes(5), Simon P. Robinson(5), Mahesh Mistry(5), Justin K. Wyatt(5), J Bozek(4), Gary W. Plourde(4), Stephen T. Newman(4), B V Potter(4), M J Reed(4)