Padmaja Yalamanchili

Pfeiffer Medical Center — United States

Medicine · Health Sciences

18h-index1.6kcitations27works5.02yr avg
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Research Topics

Cell Adhesion Molecules Research(6), Cardiac Imaging and Diagnostics(5), Peptidase Inhibition and Analysis(5), Advanced MRI Techniques and Applications(4), Viral Infections and Immunology Research(4)

Publications27 total

AAV-mediated allele-specific silencing alleviates neuropathology in a novel non-human primate model of Spinocerebellar ataxia type 3
2025Open Access
Preclinical studies of gene replacement therapy for CDKL5 deficiency disorder
Molecular Therapy·2024· 10 citedOpen Access
AAV2-hAADC (Eladocagene Exuparvovec) Biodistribution and Expression: Superiority of Intraputaminal versus Intracerebroventricular and Intrathecal (Lumbar) Routes of Administration
International Journal of Toxicology·2022· 3 cited
Effect of LX4211 on Glucose Homeostasis and Body Composition in Preclinical Models
Journal of Pharmacology and Experimental Therapeutics·2014· 50 cited
Effects of Picornavirus Proteinases on Host Cell Transcription
ASM Press eBooks·2014· 13 cited
Tu1333 Lx1033, a Second Generation Locally-Acting Serotonin Synthesis Inhibitor Demonstrates Increased Potency and Favorable Safety Profile in Preclinical Studies
Gastroenterology·2012Open Access
Synthesis and Cardiac Imaging of<sup>18</sup>F-Ligands Selective for β<sub>1</sub>-Adrenoreceptors
ACS Medicinal Chemistry Letters·2011· 9 citedOpen Access
Evaluation of LMI1195, a Novel <sup>18</sup> F-Labeled Cardiac Neuronal PET Imaging Agent, in Cells and Animal Models
Circulation Cardiovascular Imaging·2011· 108 citedOpen Access
Inhibition of Sphingosine 1-Phosphate Lyase for the Treatment of Rheumatoid Arthritis: Discovery of (<i>E</i>)-1-(4-((1<i>R</i>,2<i>S</i>,3<i>R</i>)-1,2,3,4-Tetrahydroxybutyl)-1<i>H</i>-imidazol-2-yl)ethanone Oxime (LX2931) and (1<i>R</i>,2<i>S</i>,3<i>R</i>)-1-(2-(Isoxazol-3-yl)-1<i>H</i>-imidazol-4-yl)butane-1,2,3,4-tetraol (LX2932)
Journal of Medicinal Chemistry·2010· 110 cited
Molecular Imaging of Matrix Metalloproteinase in Atherosclerotic Lesions
Journal of the American College of Cardiology·2008· 131 citedOpen Access
Assessment of 18F-labeled mitochondrial complex I inhibitors as PET myocardial perfusion imaging agents in rats, rabbits, and primates
European Journal of Nuclear Medicine and Molecular Imaging·2008· 36 cited
ChemInform Abstract: Amino Acid Derived Enamides: Synthesis and Aminopeptidase Activity.
ChemInform·2008
Synthesis and Biological Evaluation of Pyridazinone Analogues as Potential Cardiac Positron Emission Tomography Tracers
Journal of Medicinal Chemistry·2008· 44 cited
Amino Acid Derived Enamides:  Synthesis and Aminopeptidase Activity
Organic Letters·2007· 51 cited
Mechanism of uptake and retention of F-18 BMS-747158-02 in cardiomyocytes: A novel PET myocardial imaging agent
Journal of Nuclear Cardiology·2007· 158 cited
Abstract 1914: BMS753951: A Novel Low Molecular Weight Magnetic Resonance Contrast Agent Selective For Arterial Wall Imaging
Circulation·2007· 8 cited
Synthesis and Biological Evaluation of the Mitochondrial Complex 1 Inhibitor 2-[4-(4-Fluorobutyl)benzylsulfanyl]-3-methylchromene-4-one as a Potential Cardiac Positron Emission Tomography Tracer
Journal of Medicinal Chemistry·2007· 11 cited
Radiolabeled Divalent Peptidomimetic Vitronectin Receptor Antagonists as Potential Tumor Radiotherapeutic and Imaging Agents
Bioconjugate Chemistry·2007· 19 cited
Structure−Activity Relationships of <sup>111</sup>In- and <sup>99m</sup>Tc-Labeled Quinolin-4-one Peptidomimetics as Ligands for the Vitronectin Receptor:  Potential Tumor Imaging Agents
Bioconjugate Chemistry·2006· 28 cited
Noninvasive Targeted Imaging of Matrix Metalloproteinase Activation in a Murine Model of Postinfarction Remodeling
Circulation·2005· 201 citedOpen Access
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Frequent Co-authors

Michael Azure(9), David S. Casebier(9), Simon P. Robinson(8), Megan Hayes(7), Ming Yu(6), Mikhail Kagan(6), Heike Radeke(6), Ajay Purohit(5), Thomas D. Harris(5), Mary Guaraldi(5), Joel Lazewatsky(5), David S. Edwards(4), Richard R. Cesati(4), J Bozek(3), William E. Heydorn(3), Alan Wilson(3), David Onthank(3), Judit Bartis(3), Charles Ellars(3), John Barrett(3)