S.S. Thorgeirsson

Medicine · Health Sciences

23h-index2.5kcitations64works0.02yr avg
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Research Topics

Liver physiology and pathology(15), Carcinogens and Genotoxicity Assessment(12), Drug Transport and Resistance Mechanisms(8), Pharmacogenetics and Drug Metabolism(7), DNA Repair Mechanisms(5)

Publications63 total

Application of patient-derived liver cancer cells for personalized treatment approach: from phenotypic characterization to therapeutic target identification
Journal of Hepatology·2018
Transient Expansion of Stem-Like Tumor-Initiating Cells Contributes to Chemoresistance during Anti-Angiogenic Therapies in Hepatocellular Carcinomas
Journal of Hepatology·2016
Activation of hepatic stem-like cells in the tumor microenvironment is a critical determinant of the prognosis of HCC patients
Zeitschrift für Gastroenterologie·2015
O100 : The hepatic microenvironment induces a CSC phenotype and determines the prognosis of HCC patients
Journal of Hepatology·2015
The hepatic tumor microenvironment is important for the CSC phenotype and progression of liver cancer
Zeitschrift für Gastroenterologie·2015
P69 IMPACT OF EPIGENETIC REPROGRAMMING ON HEPATIC TUMORIGENIC PROPERTIES
Journal of Hepatology·2014
1078 MECHANIC-BASED REPROGRAMMING OF HEPATIC SELF-RENEWING TUMOR-INITIATING CELLS THROUGH DNMT1-INHIBITION
Journal of Hepatology·2013Open Access
T-53 Mechanic-based reprogramming of hepatic self-renewing tumor-initiating cells through DNMT1-inhibition
Digestive and Liver Disease·2013
113 KERATIN19: A KEY ROLE PLAYER IN THE INVASION OF HUMAN HEPATOCELLULAR CARCINOMAS WITH PROGENITOR CELL FEATURES
Journal of Hepatology·2012· 1 cited
385 MOLECULAR STAGES OF PDGFB DRIVEN LIVER FIBROSIS: LESONS FROM A TRANSGENIC MOUSE MODEL
Journal of Hepatology·2012· 1 cited
290 INTEGRATIVE ANALYSIS OF SIRT6 REGULATED GENE NETWORKS IN THE DEVELOPMENT AND PROGRESSION OF HUMAN HEPATOCELLULAR CARCINOMA
Journal of Hepatology·2012
Genetic signatures shared in embryonic liver development and liver cancer define prognostically relevant subgroups in HCC
Zeitschrift für Gastroenterologie·2011· 2 cited
113 MODULATION OF DEMETHYLATION AND ANTITUMOR POTENTIAL OF ZEBULARINE IN LIVER CANCER
Journal of Hepatology·2009Open Access
The role of decorin in liver fibrogenesis
Zeitschrift für Gastroenterologie·2006
Activation of beta-catenin pathway in human hepatocellular carcinoma negatively correlates to CD-44 and AFP expression
Journal of Hepatology·2003
113 Mice with hepatocye-specific disruption of transforming growth factor beta (TGF-β) signaling have enhanced mitogenic response during liver regeneration
Hepatology·2003
264 NF-KB and STAT-3 are required for hepatic stem cell activation
Hepatology·2003· 1 cited
272 In vitro differentiation of adult liver stem cells into the hepatocytic lineage
Hepatology·2003· 1 cited
819 Conditional ablation of reveals an essential role in liver repair after injury
Hepatology·2003
Activation of beta-catenin during hepatocarcinogenesis in transgenic mouse models: relationship to phenotype and tumor grade.
PubMed·2001· 93 cited
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Frequent Co-authors

Richard H. Adamson(5), Herman A.J. Schut(5), H.C. Bisgaard(3), Elizabeth G. Snyderwine(3), T Sugimura(3), Alan R. Boobis(3), Valentina M. Factor(3), Michael E. McManus(3), Peter J. Wirth(3), Anthony C. Huggett(3), Peter R. Galle(3), Jens U. Marquardt(3), P Nagy(2), Unnur P. Thorgeirsson(2), D W Nebert(2), Timothy W. Gant(2), Ritva P. Evarts(2), E R Marsden(2), Chu Chieh Hsia(2), Harold A. Dunsford(2)