Mark O. Urban

Northwestern University — United States

Medicine · Health Sciences

20h-index1.5kcitations33works0.02yr avg
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Research Topics

Pain Mechanisms and Treatments(17), Ion channel regulation and function(11), Neuropeptides and Animal Physiology(6), Cannabis and Cannabinoid Research(5), Ion Channels and Receptors(5)

Publications33 total

ACNP 59th Annual Meeting: Poster Session III
Neuropsychopharmacology·2020· 4 citedOpen Access
Identification of second-generation P2X3 antagonists for treatment of pain
Bioorganic & Medicinal Chemistry Letters·2018· 12 citedOpen Access
Benzoxazolinone aryl sulfonamides as potent, selective Nav1.7 inhibitors with in vivo efficacy in a preclinical pain model
Bioorganic & Medicinal Chemistry Letters·2017· 36 citedOpen Access
Discovery of selective, orally bioavailable, N-linked arylsulfonamide Nav1.7 inhibitors with pain efficacy in mice
Bioorganic & Medicinal Chemistry Letters·2017· 45 citedOpen Access
Bioavailable pyrrolo-benzo-1,4-diazines as Nav1.7 sodium channel blockers for the treatment of pain
Bioorganic & Medicinal Chemistry Letters·2014· 15 citedOpen Access
MK-8825: A potent and selective CGRP receptor antagonist with good oral activity in rats
Bioorganic & Medicinal Chemistry Letters·2012· 27 citedOpen Access
fMRI of pain processing in the brain: A within-animal comparative study of BOLD vs. CBV and noxious electrical vs. noxious mechanical stimulation in rat
NeuroImage·2011· 45 cited
Identification of non-amidine inhibitors of acid-sensing ion channel-3 (ASIC3)
Bioorganic & Medicinal Chemistry Letters·2011· 17 citedOpen Access
Discovery of 3-Substituted Aminocyclopentanes as Potent and Orally Bioavailable NR2B Subtype-Selective NMDA Antagonists
ACS Chemical Neuroscience·2011· 24 cited
Imidazopyridine CB2 agonists: Optimization of CB2/CB1 selectivity and implications for in vivo analgesic efficacy
Bioorganic & Medicinal Chemistry Letters·2011· 56 citedOpen Access
Decahydroquinoline amides as highly selective CB2 agonists: Role of selectivity on in vivo efficacy in a rodent model of analgesia
Bioorganic & Medicinal Chemistry Letters·2011· 20 citedOpen Access
Reversal of acid‐induced and inflammatory pain by the selective ASIC3 inhibitor, APETx2
British Journal of Pharmacology·2010· 123 citedOpen Access
Induced Proteinuria And Hematuria Is Transient: Effects Of Long Distance Bicycling Between Diabetics And Non-diabetics
Medicine & Science in Sports & Exercise·2010
Large Animal Models for Pain Therapeutic Development
Frontiers in neuroscience·2009· 15 cited
Synthesis, Structure−Activity Relationship, and Pharmacological Profile of Analogs of The ASIC-3 Inhibitor A-317567
ACS Chemical Neuroscience·2009· 37 cited
Antinociceptive effects of the non-selective cannabinoid receptor agonist CP 55,940 are absent in CB1−/− and not CB2−/− mice in models of acute and persistent pain
Neuropharmacology·2009· 47 cited
Amidine derived inhibitors of acid-sensing ion channel-3 (ASIC3)
Bioorganic & Medicinal Chemistry Letters·2009· 49 cited
The Effect of Amitriptyline on Ectopic Discharge of Primary Afferent Fibers in the L5 Dorsal Root in a Rat Model of Neuropathic Pain
Anesthesia & Analgesia·2009· 10 cited
Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3)
Bioorganic & Medicinal Chemistry Letters·2009· 54 citedOpen Access
HC-030031, a TRPA1 Selective Antagonist, Attenuates Inflammatory- and Neuropathy-Induced Mechanical Hypersensitivity
Molecular Pain·2008· 441 citedOpen Access
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Frequent Co-authors

Stefanie A. Kane(11), Michael Leitl(8), Annie Liang(7), Matthew J. Cato(7), Sean P. Cook(6), George D. Hartman(6), Mark T. Bilodeau(6), Aneta Jovanovska(6), Darrell A. Henze(5), Robert H. Spencer(5), Scott D. Kuduk(5), Christina N. Di Marco(5), Ronald K. Chang(4), Robert M. DiPardo(4), Nova Sain(4), Eric L. Moore(3), Christopher S. Burgey(3), Rebecca B. White(3), Jacqueline Panigel(3), Jixin Wang(3)