L. J. Thal

University of Washington — United States

Medicine · Health Sciences

65h-index17.5kcitations138works0.02yr avg
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Research Topics

Alzheimer's disease research and treatments(48), Dementia and Cognitive Impairment Research(45), Cholinesterase and Neurodegenerative Diseases(24), Neuroscience and Neuropharmacology Research(14), Parkinson's Disease Mechanisms and Treatments(11)

Publications137 total

Alterations in CSF Amyloid-β and Tau Biomarkers in Former College and Professional American Football Players: Findings from the DIAGNOSE CTE Research Project
Journal of Neurotrauma·2026
Alzheimer Disease–Relevant Biomarker Elevations in Psychosis and Broad Neuropsychiatric Impairment
JAMA Psychiatry·2026Open Access
The Binding Patterns of Neurofibrillary Tangles Observed With High‐Resolution Autoradiography of <sup>18</sup> F MK 6240 and <sup>18</sup> F AV1451 Are Comparable and Predominantly Recognize Tangles at the Middle Stage
Alzheimer s & Dementia·2025Open Access
Impact of Age and Sex on Extra‐Brain, Off‐Target Binding in Tau PET Scans (18F‐FTP)
Alzheimer s & Dementia·2025Open Access
Periventricular white matter hyperintensities increase the likelihood of progression from amnestic mild cognitive impairment to dementia
Journal of Neurology·2008· 109 citedOpen Access
Volumetric MRI vs clinical predictors of Alzheimer disease in mild cognitive impairment
Neurology·2008· 183 cited
In dementia with Lewy bodies, Braak stage determines phenotype, not Lewy body distribution
Neurology·2007· 98 cited
Cycad exposure and risk of dementia, MCI, and PDC in the Chamorro population of Guam
Neurology·2007· 101 cited
Prevalence of dementia in Chamorros on Guam
Neurology·2007· 70 cited
Clinical predictors of progression to Alzheimer disease in amnestic mild cognitive impairment
Neurology·2007· 228 cited
APOE-E4 status, hippocampal volume and gender differences in mild cognitive impairment
2006
The BDNF val66met polymorphism is not associated with late onset Alzheimer's disease in three case–control samples
Molecular Psychiatry·2005· 37 citedOpen Access
Smoking affects the phenotype of Alzheimer disease
Neurology·2005· 37 cited
The importance of neuritic plaques and tangles to the development and evolution of AD
Neurology·2004· 480 cited
Impact of <i>APOE</i> genotype on neuropathologic and neurochemical markers of Alzheimer disease
Neurology·2004· 216 cited
Alzheimer disease without neocortical neurofibrillary tangles
Neurology·2004· 62 cited
Intraparenchymal nerve growth factor improves behavioral deficits while minimizing the adverse effects of intracerebroventricular delivery
Neuroscience·2004· 34 cited
α-1-ANTICHYMOTRYPSIN POLYMORPHISM IN THE GENE PROMOTER REGION AFFECTS SURVIVAL AND SYNAPSIS LOSS IN ALZHEIMER’S DISEASE
Archives of Gerontology and Geriatrics·2004· 7 cited
Idebenone treatment fails to slow cognitive decline in Alzheimer’s disease
Neurology·2003· 155 cited
Neuromotor abnormalities and risk for psychosis in Alzheimer’s disease
Neurology·2003· 11 cited
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Frequent Co-authors

Lawrence A. Hansen(12), David P. Salmon(9), Eliezer Masliah(8), Jody Corey‐Bloom(8), Douglas Galasko(7), Michael Alford(6), Ronald G. Thomas(6), C. Richard Hofstetter(6), Robert Katzman(5), John Olichney(5), Michael Grundman(5), Mary Sano(5), Pietro Tiraboschi(4), Kimberly Schafer(4), Murray A. Raskind(4), Robert Katzman(4), Fred H. Gage(4), Peter J. Whitehouse(3), Melville R. Klauber(3), Nelson Butters(3)