Richard Clothier

Fund for the Replacement of Animals in Medical Experiments — United Kingdom

Veterinary · Health Sciences

19h-index1.6kcitations70works0.02yr avg
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Research Topics

Animal testing and alternatives(36), Computational Drug Discovery Methods(10), 3D Printing in Biomedical Research(9), Carcinogens and Genotoxicity Assessment(7), Effects and risks of endocrine disrupting chemicals(7)

Publications70 total

Non-animal Replacements for Acute Toxicity Testing
Alternatives to Laboratory Animals·2015· 9 cited
Comparative analysis of eight cytotoxicity assays evaluated within the ACuteTox Project
Toxicology in Vitro·2012· 40 cited
The Development and Evaluation of <i>In Vitro</i> Alternative Assays: A Personal Perspective
Alternatives to Laboratory Animals·2010· 1 citedOpen Access
A Frame Response to the European Commission Consultation on the <i>Draft Report on Alternative (Non-animal) Methods for Cosmetics Testing: Current Status and Future Prospects — 2010</i>
Alternatives to Laboratory Animals·2010· 11 cited
Seeing within: art and the study of anatomy
Lincoln Repository (University of Lincoln)·2010
FRAME and the Validation Process
Alternatives to Laboratory Animals·2009· 4 citedOpen Access
A proposed eye irritation testing strategy to reduce and replace in vivo studies using Bottom–Up and Top–Down approaches
Toxicology in Vitro·2009· 210 cited
A Database of IC50 Values and Principal Component Analysis of Results from Six Basal Cytotoxicity Assays, for Use in the Modelling of the <i>In Vivo</i> and <i>In Vitro</i> Data of the EU ACuteTox Project
Alternatives to Laboratory Animals·2008· 31 citedOpen Access
Comparative evaluation of cytotoxicity and phototoxicity of mono and diacylglycerol amino acid-based surfactants
Food and Chemical Toxicology·2008· 19 citedOpen Access
Estimation of human blood LC50 values for use in modeling of in vitro–in vivo data of the ACuteTox project
Toxicology in Vitro·2008· 52 cited
Fluorescein Leakage Assay Background Review Document As An Alternative Method for Eye Irritation Testing
2008· 4 cited
Identification and manipulation of transglutaminase isoforms and activity for the detection of squamous metaplasia in tracheobronchial cells in vitro
Toxicology·2007
The Principles of Weight of Evidence Validation of Test Methods and Testing Strategies
Alternatives to Laboratory Animals·2006· 61 citedOpen Access
Normal human keratinocyte assay to predict the human irritancy response
Nature Protocols·2006· 4 cited
The FRAME Alternatives Laboratory Database. 1. <i>In Vitro</i> Basal Cytotoxicity determined by the Kenacid Blue Total Protein Assay
Alternatives to Laboratory Animals·2006· 8 cited
Modelling long-term repeat-dose toxicity - Challenges faced
Bristol Research (University of Bristol)·2006· 1 cited
Vote of Thanks for Professor Alan Goldberg's Sixth Annual FRAME Lecture
Alternatives to Laboratory Animals·2004
Assessment of the potential irritation and photoirritation of novel amino acid-based surfactants by in vitro methods as alternative to the animal tests
Toxicology·2004· 47 cited
The Third FRAME Toxicity Committee: Working toward Greater Implementation of Alternatives in Toxicity Testing
Alternatives to Laboratory Animals·2004· 7 cited
166 Preliminary (Phase I) results of a validation study to evaluate the reliability and relevance of two in vitro cytotoxicity assays for predicting rodent and human acute systemic toxicity
Toxicology Letters·2003
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Frequent Co-authors

Michael Balls(20), Paul J. Dierickx(6), Rodger Curren(5), Björn Ekwall(5), Sandra Coecke(5), U. Kristen(4), Cecilia Clemedson(4), Geirid Fiskesjö(4), Lourdes Garza‐Ocañas(4), Michael Sjöstróm(4), Robert D. Combes(4), Horst Spielmann(3), U. Pfannenbecker(3), Dariusz Śladowski(3), John W. Harbell(3), Thomas Härtung(3), Marı́a Pilar Vinardell(3), Nancy Khammo(3), Elisabeth McFarlane-Abdulla(3), Frank A. Barile(3)