Magdeleine Hung

Gilead Sciences (United States) — United States

Medicine · Health Sciences

26h-index2.4kcitations51works1.22yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

HIV/AIDS drug development and treatment(21), HIV Research and Treatment(16), Hepatitis C virus research(15), Hepatitis B Virus Studies(13), Monoclonal and Polyclonal Antibodies Research(8)

Publications51 total

The therapeutic antibody sacituzumab induces trophoblast cell-surface antigen-2 conformational rearrangement
Structure·2025
A highly selective TCR-mimic antibody reveals unexpected mechanisms of HBV peptide-MHC recognition and previously unknown target biology
mAbs·2025Open Access
Development of a PRAME pMHC targeted T cell engager for solid tumor therapy
mAbs·2025Open Access
Identification and engineering of potent bispecific antibodies that protect against herpes simplex virus recurrent disease
Cell Reports·2025· 2 citedOpen Access
Flt3 agonist enhances immunogenicity of arenavirus vector-based simian immunodeficiency virus vaccine in macaques
Journal of Virology·2024· 4 citedOpen Access
Effects of small molecule-induced dimerization on the programmed death ligand 1 protein life cycle
Scientific Reports·2022· 16 citedOpen Access
HIV envelope antibodies and TLR7 agonist partially prevent viral rebound in chronically SHIV-infected monkeys
PLoS Pathogens·2022· 31 citedOpen Access
847 Pharmacokinetics and pharmacodynamics of GS-3583 in cynomolgus monkeys
Regular and Young Investigator Award Abstracts·2021· 1 citedOpen Access
846 Pre-clinical validation of a FLT3L-fusion protein for dendritic cell expansion and anti-tumor efficacy
Regular and Young Investigator Award Abstracts·2021· 1 citedOpen Access
Clinical targeting of HIV capsid protein with a long-acting small molecule
Nature·2020· 394 citedOpen Access
Toll‐Like Receptor 8 Agonist GS‐9688 Induces Sustained Efficacy in the Woodchuck Model of Chronic Hepatitis B
Hepatology·2020· 69 citedOpen Access
Hepatitis B core-specific memory B cell responses associate with clinical parameters in patients with chronic HBV
Journal of Hepatology·2020· 62 cited
Elucidating molecular interactions of L-nucleotides with HIV-1 reverse transcriptase and mechanism of M184V-caused drug resistance
Communications Biology·2019· 26 citedOpen Access
PD-1 Blockade and TLR7 Activation Lack Therapeutic Benefit in Chronic Simian Immunodeficiency Virus-Infected Macaques on Antiretroviral Therapy
Antimicrobial Agents and Chemotherapy·2019· 59 citedOpen Access
A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model
Nature Medicine·2019· 158 citedOpen Access
Comparative characterization of B cells specific for HBV nucleocapsid and envelope proteins in patients with chronic hepatitis B
Journal of Hepatology·2019· 92 cited
Spatiotemporal Analysis of Hepatitis B Virus X Protein in Primary Human Hepatocytes
Journal of Virology·2019· 46 citedOpen Access
FRI-153-Potent hepatitis B core-specific B cell responses associate with clinical parameters in untreated and virally suppressed chronic HBV patients
Journal of Hepatology·2019· 1 cited
Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor
Bioorganic & Medicinal Chemistry·2018· 16 citedOpen Access
PD-1 blockade partially recovers dysfunctional virus–specific B cells in chronic hepatitis B infection
Journal of Clinical Investigation·2018· 265 citedOpen Access
page 1 of 3Next →

Frequent Co-authors

Roman Sakowicz(16), Debi Jin(15), Anita Niedziela‐Majka(15), Nikolai Novikov(10), Xiaohong Liu(10), Katherine M. Brendza(10), E.B. Lansdon(8), Nikos Pagratis(7), Romas Geleziunas(7), Leanna Lagpacan(7), Melanie Wong(6), Latesh Lad(6), Simon P. Fletcher(6), Ruth Wang(6), Manuel Tsiang(6), Brian Carr(6), Giuseppe A. Papalia(5), Stephanie A. Leavitt(5), Dharmaraj Samuel(5), Mark Nagel(5)