Lang Ngo

Memorial Sloan Kettering Cancer Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index3.0kcitations24works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Histone Deacetylase Inhibitors Research(15), Epigenetics and DNA Methylation(11), Protein Degradation and Inhibitors(6), Cancer-related Molecular Pathways(4), RNA modifications and cancer(4)

Publications24 total

Creation of a histone deacetylase 6 inhibitor and its biological effects
Proceedings of the National Academy of Sciences·2015· 36 citedOpen Access
Development of a histone deacetylase 6 inhibitor and its biological effects
Proceedings of the National Academy of Sciences·2013· 132 citedOpen Access
Abstract LB-308: Development of histone deacetylase 6 inhibitors: Effects of HDAC6 inhibitors in normal and cancer cells.
Cancer Research·2013
Role of checkpoint kinase 1 (Chk1) in the mechanisms of resistance to histone deacetylase inhibitors
Proceedings of the National Academy of Sciences·2011· 51 citedOpen Access
Abstract A206: Chk1 protects normal cells from HDAC inhibitor-induced cell death.
Molecular Cancer Therapeutics·2011
Mumps Antibody Levels Among Students Before a Mumps Outbreak: In Search of a Correlate of Immunity
The Journal of Infectious Diseases·2011· 84 cited
Selective inhibition of histone deacetylase 6 (HDAC6) induces DNA damage and sensitizes transformed cells to anticancer agents
Proceedings of the National Academy of Sciences·2010· 201 citedOpen Access
Histone deacetylase inhibitor induces DNA damage, which normal but not transformed cells can repair
Proceedings of the National Academy of Sciences·2010· 376 citedOpen Access
Abstract LB-33: Selective inhibition of Histone Deacetylase 6 enhances transformed cell sensitivity to anti-cancer agents
Cancer Research·2010
Abstract LB-55: Histone deacetylase inhibitor causes DNA damage and apoptosis by downregulation of repair enzymes in cancer but not normal cells: Basis of resistance of normal cells to HDACi
Cancer Research·2010
Histone deacetylase inhibitors selectively suppress expression of HDAC7
Molecular Cancer Therapeutics·2007· 97 cited
Intrinsic apoptotic and thioredoxin pathways in human prostate cancer cell response to histone deacetylase inhibitor
Proceedings of the National Academy of Sciences·2006· 179 citedOpen Access
Role of pro- and anti-apoptotic proteins in prostate cancer cells sensitive and resistant to histone deacetylase inhibitor induced cell death
Cancer Research·2006
Induction of Polyploidy by Histone Deacetylase Inhibitor: A Pathway for Antitumor Effects
Cancer Research·2005· 120 citedOpen Access
Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors
Proceedings of the National Academy of Sciences·2005· 504 citedOpen Access
Histone deacetylase (HDAC) inhibitor activation of p21 <sup>WAF1</sup> involves changes in promoter-associated proteins, including HDAC1
Proceedings of the National Academy of Sciences·2004· 550 citedOpen Access
Cloning of the cDNA encoding phenylalanyl tRNA synthetase regulatory α-subunit-like protein whose expression is down-regulated during differentiation
Gene·1999· 9 cited
Photoaffinity Labeling and Mass Spectrometry Identify Ribosomal Protein S3 as a Potential Target for Hybrid Polar Cytodifferentiation Agents
Journal of Biological Chemistry·1999· 36 citedOpen Access
Second generation hybrid polar compounds are potent inducers of transformed cell differentiation.
Proceedings of the National Academy of Sciences·1996· 420 citedOpen Access
Changes in p34cdc2 kinase activity and cyclin A during induced differentiation of murine erythroleukemia cells.
PubMed·1992· 18 cited
page 1 of 2Next →

Frequent Co-authors

Paul A. Marks(16), Megan L. Choy(7), P A Marks(6), Ronald Breslow(6), Gisela Venta-Perez(6), Weisheng Xu(5), Richard A. Rifkind(5), Victoria M. Richon(4), Milos Dokmanovic(4), Gisela Perez(4), Ju‐Hee Lee(4), Adaickapillai Mahendran(3), Yuanshan Yao(3), Hiroaki Kiyokawa(3), Weili Xu(2), Yael Webb(2), B Jursic(2), R A Rifkind(2), Steven S. Foster(2), Mandana Namdar(2)