Mohan Kuppuswamy

Saint Louis University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index1.2kcitations23works0.02yr avg
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Research Topics

Virus-based gene therapy research(21), Viral Infectious Diseases and Gene Expression in Insects(11), Viral gastroenteritis research and epidemiology(6), CAR-T cell therapy research(6), Cancer Research and Treatments(6)

Publications23 total

Functional Similarity between E6 Proteins of Cutaneous Human Papillomaviruses and the Adenovirus E1A Tumor-Restraining Module
Journal of Virology·2013· 7 citedOpen Access
Adenovirus Type 5 E1A and E6 Proteins of Low-Risk Cutaneous Beta-Human Papillomaviruses Suppress Cell Transformation through Interaction with FOXK1/K2 Transcription Factors
Journal of Virology·2010· 49 cited
Preparation and Titration of CsCl-Banded Adenovirus Stocks
Humana Press eBooks·2007· 106 cited
642. Toxicological Findings with Oncolytic Adenovirus Vector VRX-007, Wild-Type Ad5, and a Replication-Defective Adenovirus Vector in Syrian Hamsters and C57BL/6 Mice
Molecular Therapy·2006Open Access
651. VRX-007, an Oncolytic Adenovirus Vector, Replicates in Syrian Hamsters but Not Mice: Comparison of Biodistribution Studies Performed in the Syrian Hamster and Mouse
Molecular Therapy·2006
Cotton Rat Tumor Model for the Evaluation of Oncolytic Adenoviruses
Human Gene Therapy·2005· 65 cited
Brief Report Cotton Rat Tumor Model for the Evaluation of Oncolytic Adenoviruses
2005
Adenovirus immunoregulatory E3 proteins prolong transplants of human cells in immunocompetent mice
Virus Research·2004· 13 cited
Adenovirus E3-6.7K Protein Is Required in Conjunction with the E3-RID Protein Complex for the Internalization and Degradation of TRAIL Receptor 2
Journal of Virology·2004· 34 citedOpen Access
An Oncolytic Adenovirus Vector Combining Enhanced Cell-to-Cell Spreading, Mediated by the ADP Cytolytic Protein, with Selective Replication in Cancer Cells with Deregulated <b> <i>Wnt</i> </b> Signaling
Cancer Research·2004· 52 citedOpen Access
Radiation increases the activity of oncolytic adenovirus cancer gene therapy vectors that overexpress the ADP (E3-11.6K) protein
Cancer Gene Therapy·2003· 37 cited
Overexpression of the ADP (E3-11.6K) Protein Increases Cell Lysis and Spread of Adenovirus
Virology·2003· 122 cited
Construction and Characterization of E1-Minus Replication-Defective Adenovirus Vectors that Express E3 Proteins from the E1 Region
Virology·2002· 7 cited
Adenovirus replication–competent vectors (KD1, KD3) complement the cytotoxicity and transgene expression from replication-defective vectors (Ad-GFP, Ad-Luc)
Cancer Gene Therapy·2002· 18 cited
Inhibition of TRAIL-Induced Apoptosis and Forced Internalization of TRAIL Receptor 1 by Adenovirus Proteins
Journal of Virology·2001· 112 citedOpen Access
Tissue-Specific, Tumor-Selective, Replication-Competent Adenovirus Vector for Cancer Gene Therapy
Journal of Virology·2001· 117 citedOpen Access
Role of GATA Motifs in Tissue Factor Pathway Inhibitor Gene Expression in Malignant Cells
Thrombosis Research·2001· 9 cited
Tumor-Specific, Replication-Competent Adenovirus Vectors Overexpressing the Adenovirus Death Protein
Journal of Virology·2000· 206 citedOpen Access
Immune responses to adenoviruses: viral evasion mechanisms and their implications for the clinic
Current Opinion in Immunology·1999· 183 cited
Adenovirus inhibition of immune-mediated apoptosis
Clinical Immunology Newsletter·1999· 2 cited
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Frequent Co-authors

Konstantin Doronin(17), William S.M. Wold(17), Károly Tóth(16), Ann E. Tollefson(16), Drew L. Lichtenstein(9), Péter Krajcsi(4), G. Chinnadurai(4), Peter A. Ward(3), Elena V. Shashkova(3), Jacqueline F. Spencer(3), T. Subramanian(3), Oksana A. Doronina(2), Marie C. La Regina(2), Gregory A. Prince(2), Baoling Ying(2), S. Vijayalingam(2), Ling‐Jun Zhao(2), Darren R. Tyson(2), Debabrata Patra(2), Debanjan Dhar(2)