Leonard M. Schechtman

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index2.4kcitations57works135.02yr avg
OpenAlex↗Google Scholar↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Carcinogens and Genotoxicity Assessment(26), Effects and risks of endocrine disrupting chemicals(14), Animal testing and alternatives(10), Virus-based gene therapy research(6), Viral Infectious Diseases and Gene Expression in Insects(6)

Publications57 total

Correlation of in vitro growth properties and tumorigenicity of Syrian hamster cell lines
PubMed·2024· 135 citedOpen Access
JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for the detection of genotoxic carcinogens: I. Summary of pre-validation study results
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·2015· 24 cited
JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·2015· 86 cited
The JaCVAM international validation study on the in vivo comet assay: Selection of test chemicals
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·2015· 16 cited
Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·2012· 48 cited
Rodent cell transformation assays—A brief historical perspective
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·2012· 24 cited
ECVAM prevalidation study on in vitro cell transformation assays: General outline and conclusions of the study
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·2011· 63 cited
Cell transformation assays for prediction of carcinogenic potential: state of the science and future research needs
Mutagenesis·2011· 85 citedOpen Access
International Validation study of the in Vitro Alkaline Comet Assay
Alternatives to animal testing and experimentation : AATEX·2009
Points of Reference in the Validation Process
Alternatives to Laboratory Animals·2008· 39 cited
Guidance on Good Cell Culture Practice
2007· 87 cited
The Principles of Weight of Evidence Validation of Test Methods and Testing Strategies
Alternatives to Laboratory Animals·2006· 61 citedOpen Access
Meeting Report: Validation of Toxicogenomics-Based Test Systems: ECVAM–ICCVAM/NICEATM Considerations for Regulatory Use
Environmental Health Perspectives·2005· 69 citedOpen Access
Guidance on Good Cell Culture Practice
Alternatives to Laboratory Animals·2005· 354 cited
The FDA's Regulatory Role in the ICCVAM Process
Alternatives to Laboratory Animals·2004· 4 cited
Summary of major conclusions
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·2003· 5 cited
Strategy for genotoxicity testing and stratification of genotoxicity test results—report on initial activities of the IWGT Expert Group
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·2003· 35 cited
ECVAM-ICCVAM: Prospects for Future Collaboration
Alternatives to Laboratory Animals·2002· 7 citedOpen Access
The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM): A Review of the ICCVAM Test Method Evaluation Process and Current International Collaborations with the European Centre for the Validation of Alternative Methods (ECVAM)
Alternatives to Laboratory Animals·2002· 36 cited
Implementation of the 3Rs (Refinement, Reduction, and Replacement): Validation and Regulatory Acceptance Considerations for Alternative Toxicological Test Methods
ILAR Journal·2002· 94 citedOpen Access
page 1 of 3Next →

Frequent Co-authors

Richard E. Kouri(12), Ronald A. Lubet(10), Makoto Hayashi(9), William S. Stokes(8), Raffaella Corvi(7), Donald L. Putman(7), Thomas Härtung(6), Sandra Coecke(5), David H. Blakey(5), Laura Gribaldo(5), John T. McCarvill(5), Raymond W. Nims(4), Lutz Müller(4), Toshio Sofuni(4), Takeshi Morita(4), Raymond R. Tice(4), Sebastian Hoffmann(4), Michael Balls(3), Gregory S. Probst(3), Hiroyasu Shimada(3)