Tom Horan

Amgen (United States) — United States

Immunology and Microbiology · Life Sciences

17h-index2.8kcitations19works0.02yr avg
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Research Topics

T-cell and B-cell Immunology(7), Immune Cell Function and Interaction(7), Immunotherapy and Immune Responses(6), Asthma and respiratory diseases(2), Epilepsy research and treatment(2)

Publications19 total

Human Dickkopf‐1 (huDKK1) protein: Characterization of glycosylation and determination of disulfide linkages in the two cysteine‐rich domains
Protein Science·2011· 17 citedOpen Access
Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury
Journal of Bone and Mineral Research·2011· 120 cited
Defining dose–response relationships in the therapeutic blockade of B7RP-1-dependent immune responses
European Journal of Pharmacology·2009· 10 cited
CD28 and ICOS play complementary non-overlapping roles in the development of Th2 immunity in vivo
Cellular Immunology·2009· 17 citedOpen Access
Paradoxical role of programmed death‐1 ligand 2 in Th2 immune responses <i>in vitro</i> and in a mouse asthma model <i>in vivo</i>
European Journal of Immunology·2004· 51 citedOpen Access
The B7 family member B7-H3 preferentially down-regulates T helper type 1–mediated immune responses
Nature Immunology·2003· 568 cited
Potent activity of soluble B7RP‐1‐Fc in therapy of murine tumors in syngeneic hosts
International Journal of Cancer·2002· 33 citedOpen Access
Essential Role of NF-κB-Inducing Kinase in T Cell Activation Through the TCR/CD3 Pathway
The Journal of Immunology·2002· 79 citedOpen Access
A Role for Inducible Costimulator Protein in the CD28- Independent Mechanism of Resistance to <i>Toxoplasma gondii</i>
The Journal of Immunology·2002· 59 cited
Identification of a Heregulin Binding Site in HER3 Extracellular Domain
Journal of Biological Chemistry·2001· 45 citedOpen Access
Stimulatory Effects of B7-Related Protein-1 on Cellular and Humoral Immune Responses in Mice
The Journal of Immunology·2001· 45 citedOpen Access
ICOS is essential for effective T-helper-cell responses
Nature·2001· 664 cited
Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS
International Immunology·2000· 134 citedOpen Access
T-cell co-stimulation through B7RP-1 and ICOS
Nature·1999· 760 cited
Conformational Changes in G-CSF/Receptor Complex As Investigated by Isotope-Edited FTIR Spectroscopy
Biochemistry·1997· 20 cited
A light scattering/size exclusion chromatography method for studying the stoichiometry of a protein-protein complex
Techniques in protein chemistry·1996· 10 cited
Dimerization of the Extracellular Domain of Granulocyte-Colony Stimulating Factor Receptor by Ligand Binding:  A Monovalent Ligand Induces 2:2 Complexes
Biochemistry·1996· 61 cited
THE USE OF DILANTIN IN THE TREATMENT OF EPILEPSY
The Journal of Nervous and Mental Disease·1940· 40 cited
THE USE OF DILATIN IN THE TREATMENT OF EPILEPSY
Annals of Internal Medicine·1939· 40 cited

Frequent Co-authors

Steven K. Yoshinaga(6), John Whoriskey(4), Tadahiko Kohno(3), Gordon S. Duncan(3), Steve K. Yoshinaga(3), Tsutomu Arakawa(3), Sanjay D. Khare(2), Jane Guo(2), Marco Coccia(2), David Brankow(2), Pauline Campbell(2), Tianang Dai(2), Ariela Hui(2), Arda Shahinian(2), Gwyneth Van(2), Tak W. Mak(2), Giorgio Senaldi(2), Manel Jordana(2), Andrew Wakeham(2), Annick Itié(2)