Stephen J. Demosky

National Institutes of Health — United States

Medicine · Health Sciences

24h-index2.1kcitations49works0.02yr avg
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Research Topics

Cholesterol and Lipid Metabolism(26), Lipoproteins and Cardiovascular Health(17), Diabetes, Cardiovascular Risks, and Lipoproteins(11), Cancer, Lipids, and Metabolism(10), Drug Transport and Resistance Mechanisms(7)

Publications49 total

Apolipoprotein C-II Mimetic Peptide Promotes the Plasma Clearance of Triglyceride-Rich Lipid Emulsion and the Incorporation of Fatty Acids into Peripheral Tissues of Mice
Journal of Nutrition and Metabolism·2019· 17 citedOpen Access
Development of a novel fluorescent activity assay for lecithin:cholesterol acyltransferase
Annals of Clinical Biochemistry International Journal of Laboratory Medicine·2017· 8 citedOpen Access
Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31
Journal of Pharmacology and Experimental Therapeutics·2017· 43 citedOpen Access
Abstract 556: Lipoprotein Remodeling and Cholesterol Exchange Monitored Using Fluorescent Lipids and Proteins
Arteriosclerosis Thrombosis and Vascular Biology·2017
High‐density lipoprotein reduces inflammation from cholesterol crystals by inhibiting inflammasome activation
Immunology·2016· 126 citedOpen Access
Abstract 230: Lipoprotein X Causes Renal Disease in LCAT Deficiency
Arteriosclerosis Thrombosis and Vascular Biology·2016
Abstract 226: Mechanism of LCAT Activation by Compound A
Arteriosclerosis Thrombosis and Vascular Biology·2016
Lipoprotein X Causes Renal Disease in LCAT Deficiency
PLoS ONE·2016· 85 citedOpen Access
Increased plasma cholesterol esterification by LCAT reduces diet-induced atherosclerosis in SR-BI knockout mice
Journal of Lipid Research·2015· 51 citedOpen Access
Endothelial Expression of Scavenger Receptor Class B, Type I Protects against Development of Atherosclerosis in Mice
BioMed Research International·2015· 39 citedOpen Access
A Short Synthetic Peptide Mimetic of Apolipoprotein A1 Mediates Cholesterol and Globotriaosylceramide Efflux from Fabry Fibroblasts
JIMD Reports·2015· 9 citedOpen Access
Elevated interleukin-10: A new cause of dyslipidemia leading to severe HDL deficiency
Journal of clinical lipidology·2014· 53 citedOpen Access
LCAT deficiency does not impair amyloid metabolism in APP/PS1 mice
Journal of Lipid Research·2014· 7 citedOpen Access
Abstract 110: Novel Apoc-II Mimetic Peptide Activates LPL and Decreases Serum Triglycerides in Mice.
Arteriosclerosis Thrombosis and Vascular Biology·2013
Endothelial expression of human ABCA1 in mice increases plasma HDL cholesterol and reduces diet-induced atherosclerosis
Journal of Lipid Research·2011· 54 citedOpen Access
P288 STRUCTURE–FUNCTION RELATIONSHIPS OF APOLIPOPROTEIN A-I MIMETIC PEPTIDES: IMPLICATIONS FOR ANTI-ATHEROGENIC ACTIVITIES OF HIGH DENSITY LIPOPROTEIN
Atherosclerosis Supplements·2010
5A Apolipoprotein Mimetic Peptide Promotes Cholesterol Efflux and Reduces Atherosclerosis in Mice
Journal of Pharmacology and Experimental Therapeutics·2010· 110 citedOpen Access
Abstract: P437 PHOSPHOLIPID COMPLEXATION TO THE 37PA APO MIMETIC PEPTIDE INCREASES CHOLESTEROL EFFLUX BY ABCA1 AND ABCG1 TRANSPORTERS BUT DOES NOT INCREASE IN VIVO REVERSE CHOLESTEROL TRANSPORT
Atherosclerosis Supplements·2009
Abstract 3636: The Effects of Arginase II Overexpression on Endothelial Function in Transgenic Mouse Model
Circulation·2008
Abstract 5481: Expression of Human ABCA1 in Endothelium Protects Against Diet-Induced Atherosclerosis in Mice
Circulation·2008
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Frequent Co-authors

Boris Vaisman(17), Alan T. Remaley(16), John A. Stonik(15), Jeffrey M. Hoeg(15), H Bryan Brewer(13), H. Bryan Brewer(12), Lita A. Freeman(11), Silvia Santamarina-Fojo(10), Edward B. Neufeld(9), J M Hoeg(7), Marcelo Amar(6), Alan T. Remaley(6), Seth G. Thacker(5), Alice Ossoli(5), Milton Pryor(5), Maureen Sampson(5), Robert D. Shamburek(5), A.T. Remaley(5), Catherine L. Knapper(4), Glenda D. Talley(4)