David L. DeWitt

Medicine · Health Sciences

62h-index20.7kcitations122works0.02yr avg
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Research Topics

Inflammatory mediators and NSAID effects(77), Estrogen and related hormone effects(44), Eicosanoids and Hypertension Pharmacology(22), Pharmacogenetics and Drug Metabolism(19), Steroid Chemistry and Biochemistry(15)

Publications122 total

Expression of the Human Prostaglandin Endoperoxide H Synthases:Measurement of Cyclooxygenase Activity and Inhibition by Nonsteroidal Anti-Inflammatory Drugs
2020
Secretory Leukocyte Protease Inhibitor Suppresses the Production of Monocyte Prostaglandin H Synthase-2, Prostaglandin E
2017· 3 cited
Liposomal Reconstitution of Monotopic Integral Membrane Proteins
Methods in molecular biology·2009· 4 cited
Health‐Beneficial Phenolic Aldehyde in <i>Antigonon leptopus</i> Tea
Evidence-based Complementary and Alternative Medicine·2009· 14 citedOpen Access
Anthocyanin Content, Lipid Peroxidation and Cyclooxygenase Enzyme Inhibitory Activities of Sweet and Sour Cherries
Journal of Agricultural and Food Chemistry·2009· 139 cited
Withanolide sulfoxide from Aswagandha roots inhibits nuclear transcription factor‐kappa‐B, cyclooxygenase and tumor cell proliferation
Phytotherapy Research·2009· 80 cited
Liperoxidation and Cyclooxygenase Enzyme Inhibitory Compounds from the Lipophilic Extracts of Some Culinary-Medicinal Higher Basidiomycetes Mushrooms
International journal of medicinal mushrooms·2009· 2 cited
Lipid Peroxidation, Cyclooxygenase Enzyme and Tumor Cell Proliferation Inhibitory Lignans from <i>Justicia</i> Species
Natural Product Communications·2008· 6 citedOpen Access
Non-nutritive functional agents in rattan-shoots, a food consumed by native people in the Philippines
Food Chemistry·2008· 8 cited
Health-beneficial qualities of the edible mushroom, Agrocybe aegerita
Food Chemistry·2007· 65 cited
Cultivars of Apple Fruits That Are Not Marketed with Potential for Anthocyanin Production
Journal of Agricultural and Food Chemistry·2007· 26 cited
Lipid peroxidation and cyclooxygenase enzyme inhibitory activities of acidic aqueous extracts of some dietary supplements
Phytotherapy Research·2007· 31 cited
Functional food components of Antigonon leptopus tea
Food Chemistry·2007· 39 cited
An ELISA method to measure inhibition of the COX enzymes
Nature Protocols·2006· 32 cited
The 19-amino Acid Cassette of Cyclooxygenase-2 Mediates Entry of the Protein into the Endoplasmic Reticulum-associated Degradation System
Journal of Biological Chemistry·2006· 107 citedOpen Access
Impact of Alkyl Esters of Caffeic and Ferulic Acids on Tumor Cell Proliferation, Cyclooxygenase Enzyme, and Lipid Peroxidation
Journal of Agricultural and Food Chemistry·2006· 152 cited
Topography of the Prostaglandin Endoperoxide H2 Synthase-2 in Membranes
Journal of Biological Chemistry·2006· 23 citedOpen Access
Synthetic curcuminoids modulate the arachidonic acid metabolism of human platelet 12-lipoxygenase and reduce sprout formation of human endothelial cells
Molecular Cancer Therapeutics·2006· 56 cited
Fast, efficient reconstitution of the cyclooxygenases into proteoliposomes
Archives of Biochemistry and Biophysics·2005· 16 cited
Cyclooxygenase-2 enzyme inhibitory triterpenoids from Picrorhiza kurroa seeds
Life Sciences·2005· 26 cited
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Frequent Co-authors

William L. Smith(24), Muraleedharan G. Nair(9), Elizabeth A. Meade(5), R. Michael Garavito(4), Gale M. Strasburg(4), Odette Laneuville(4), Jeffrey S. Day(3), J. Ian Gray(2), Melvin Schindler(2), Martha K. Regier(2), James Otto(2), Christopher D. Breder(2), Lawrence J. Marnett(2), Russel S. Ramsewak(2), L M Wahl(2), Jayaprakasam Bolleddula(2), Vanisree Mulabagal(2), Yanjun Zhang(2), H Wang(1), Yu-Chen Chang(1)