K H Jakobs

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index1.1kcitations30works0.02yr avg
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Research Topics

Protein Kinase Regulation and GTPase Signaling(10), Receptor Mechanisms and Signaling(7), Monoclonal and Polyclonal Antibodies Research(3), Nitric Oxide and Endothelin Effects(2), Immune Response and Inflammation(2)

Publications30 total

Gi- and Protein Kinase C-Mediated Heterologous Potentiation of Phospholipase C Signaling by G Protein-Coupled Receptors
Molecular Pharmacology·1998· 25 cited
Role of Ras/Ral signalling cascades in protein kinase C (PKC)-induced phospholipase D (PLD) stimulation
MPG.PuRe (Max Planck Society)·1998
Role of Ral GTPases in protein kinase C-induced phospholipase D stimulation
MPG.PuRe (Max Planck Society)·1998
m3 Muscarinic receptor-induced and Gi-mediated heterologous potentiation of phospholipase C stimulation: role of phosphoinositide synthesis.
Molecular Pharmacology·1996· 31 cited
Inhibition by toxin B of inositol phosphate formation induced by G protein-coupled and tyrosine kinase receptors in N1E-115 neuroblastoma cells: involvement of Rho proteins.
Molecular Pharmacology·1996· 22 cited
A distinct G(i) protein-coupled receptor for sphingosylphosphorylcholine in human leukemia HL-60 cells and human neutrophils.
Molecular Pharmacology·1996· 47 cited
Transfected muscarinic acetylcholine receptors selectively couple to Gi-type G proteins and Gq/11.
Molecular Pharmacology·1994· 171 cited
G-Proteins in the Signal Transduction of the Neutrophil
Handbook of experimental pharmacology·1993· 5 cited
Evidence for nucleoside diphosphokinase-dependent channeling of guanosine 5'-(gamma-thio)triphosphate to guanine nucleotide-binding proteins.
Molecular Pharmacology·1992· 30 cited
Complementation of formyl peptide receptor-mediated signal transduction in <i>Xenopus laevis</i> oocytes
Biochemical Journal·1992· 14 cited
Pseudomonas exotoxin A prevents beta-adrenoceptor-induced upregulation of Gi protein alpha-subunits and adenylyl cyclase desensitization in rat heart muscle cells.
Molecular Pharmacology·1990· 45 cited
Hormonal regulation of Gi alpha level and adenylyl cyclase responsiveness.
British Journal of Clinical Pharmacology·1990· 17 citedOpen Access
Mechanisms Involved in G-protein Activation by Hormone Receptors
1990
Stimulation and inhibition of adenylyl cyclase.
PubMed·1990· 11 cited
Desensitization uncouples the formyl peptide receptor-guanine nucleotide-binding protein interaction in HL60 cells.
Molecular Pharmacology·1989· 35 cited
Evidence that activation of a common G-protein by receptors for leukotriene B4 and <i>N</i>-formylmethionyl-leucyl-phenylalanine in HL-60 cells occurs by different mechanisms
Biochemical Journal·1989· 54 citedOpen Access
Molecular Mechanisms of G-Protein Activation
1989· 2 cited
Regulation of G-Protein-Mediated Signal Transfer by Ions
Journal of Cardiovascular Pharmacology·1988· 17 cited
Inhibition of Ns-stimulated human platelet adenylate cyclase by forskolin.
Molecular Pharmacology·1986· 15 cited
Mode of inhibition of renin release by angiotensin II.
PubMed·1985· 6 cited
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Frequent Co-authors

Peter Gierschik(9), Klaus Aktories(6), G. Schultz(6), Martina Schmidt(5), Thomas Wieland(4), Christopher Reithmann(4), Kenneth R. McLeish(3), Dimitrios N. Sidiropoulos(2), Karl Werdan(2), H. Schmidt‐Gayk(2), E. Hackenthal(2), Matthias Voß(2), Birgit Bauer(2), Robbert H. Cool(2), C. von Eichel-Streiber(2), Stefan Offermanns(1), Doris Homann(1), J. Sandmann(1), E Bombien(1), Karsten Spicher(1)