C. von Eichel-Streiber

Johannes Gutenberg University Mainz — Germany

Medicine · Health Sciences

16h-index2.5kcitations24works0.02yr avg
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Research Topics

Clostridium difficile and Clostridium perfringens research(21), Toxin Mechanisms and Immunotoxins(10), Botulinum Toxin and Related Neurological Disorders(4), Antimicrobial Resistance in Staphylococcus(3), Bacterial Identification and Susceptibility Testing(3)

Publications24 total

Clostridium-difficile-Ribotyp 027: Epidemiologie und Klinik des erstmaligen endemischen Auftretens in Deutschland
Zeitschrift für Gastroenterologie·2010· 7 cited
Increased number of Clostridium difficile infections and prevalence of Clostridium difficile PCR ribotype 001 in southern Germany
Eurosurveillance·2008· 56 citedOpen Access
Advances in the structural elucidation of<i>Clostridium difficile</i>toxin B using SAXS and MX techniques
Acta Crystallographica Section A Foundations of Crystallography·2008Open Access
O328 Community rather than hospital factors promote increase of Clostridium difficile associated diseases in Northern Bavaria
International Journal of Antimicrobial Agents·2007
<i>Clostridium difficile</i> Toxins Disrupt Epithelial Barrier Function by Altering Membrane Microdomain Localization of Tight Junction Proteins
Infection and Immunity·2001· 329 citedOpen Access
Nosokomiale Epidemiologie und Transmission der Clostridium-difficile-Infektion
DMW - Deutsche Medizinische Wochenschrift·2001· 1 cited
Inhibition of small G proteins of the Rho family by statins or <i>Clostridium difficile</i> toxin B enhances cytokine‐mediated induction of NO synthase II
British Journal of Pharmacology·2000· 60 citedOpen Access
A nonsense mutation abrogates production of a functional enterotoxin A in Clostridium difficile toxinotype VIII strains of serogroups F and X
FEMS Microbiology Letters·1999· 25 cited
Genetic rearrangements in the pathogenicity locus of Clostridium difficile strain 8864 – implications for transcription, expression and enzymatic activity of toxins A and B
Molecular and General Genetics MGG·1998· 64 cited
Role of Ras/Ral signalling cascades in protein kinase C (PKC)-induced phospholipase D (PLD) stimulation
MPG.PuRe (Max Planck Society)·1998
Role of Ral GTPases in protein kinase C-induced phospholipase D stimulation
MPG.PuRe (Max Planck Society)·1998
Toxins A and B from Clostridium difficile differ with respect to enzymatic potencies, cellular substrate specificities, and surface binding to cultured cells.
Journal of Clinical Investigation·1997· 152 citedOpen Access
Enterotoxin A and cytotoxin B (Clostridium difficile)
1997· 1 cited
Glucosylation of small GTP-binding Rho proteins disrupts endothelial barrier function
American Journal of Physiology-Lung Cellular and Molecular Physiology·1997· 65 cited
Pseudomembranöse Kolitis — vom Krankheitsbild zum molekularen Verständnis der Wirkung der Clostridium difficile Toxine
1996
Transient expression of RhoA, -B, and -C GTPases in HeLa cells potentiates resistance to Clostridium difficile toxins A and B but not to Clostridium sordellii lethal toxin
Infection and Immunity·1995· 58 citedOpen Access
Glucosylation of Rho proteins by Clostridium difficile toxin B
Nature·1995· 1.0k cited
The low molecular mass GTP-binding protein Rho is affected by toxin A from Clostridium difficile.
Journal of Clinical Investigation·1995· 122 citedOpen Access
Clostridium difficile toxin B acts on the GTP-binding protein Rho.
Journal of Biological Chemistry·1994· 203 citedOpen Access
Evidence for a modular structure of the homologous repetitive C-terminal carbohydrate-binding sites of Clostridium difficile toxins and Streptococcus mutans glucosyltransferases
Journal of Bacteriology·1992· 126 citedOpen Access
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Frequent Co-authors

Ingo Just(4), Klaus Aktories(4), Manfred Weidmann(3), U. Hadding(3), Jörg Selzer(2), Murielle Giry(2), Michel R. Popoff(2), Patrice Boquet(2), Stefan Borgmann(2), Manfred Kist(2), Thomas Jakobiak(2), Berit Schulte(2), Martina Schmidt(2), Matthias Voß(2), Birgit Bauer(2), Robbert H. Cool(2), K H Jakobs(2), Matthias Wilm(1), Matthias Mann(1), Asma Nusrat(1)