Ted Sharpe

Broad Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index21.4kcitations37works31.22yr avg
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Research Topics

Genomics and Phylogenetic Studies(14), Chromosomal and Genetic Variations(10), Genomic variations and chromosomal abnormalities(7), Genomics and Chromatin Dynamics(6), Genomics and Rare Diseases(6)

Publications32 total

Author Correction: Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants
Nature Communications·2024· 1 citedOpen Access
Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants
Nature Communications·2024· 26 citedOpen Access
Abstract 1220: Deep mutational scanning of EGFR reveals potential domain-specific TKI sensitivities in lung cancer and glioblastoma
Cancer Research·2024
Defining protein variant functions using high-complexity mutagenesis libraries and enhanced mutant detection software ASMv1.0
2021· 11 citedOpen Access
Author Correction: A structural variation reference for medical and population genetics
Nature·2021· 16 citedOpen Access
A structural variation reference for medical and population genetics
Nature·2020· 1.1k citedOpen Access
Mutational processes shape the landscape of TP53 mutations in human cancer
Nature Genetics·2018· 569 citedOpen Access
GATK PathSeq: a customizable computational tool for the discovery and identification of microbial sequences in libraries from eukaryotic hosts
Bioinformatics·2018· 128 citedOpen Access
SvABA: genome-wide detection of structural variants and indels by local assembly
Genome Research·2018· 456 citedOpen Access
SvABA: Genome-wide detection of structural variants and indels by local assembly
2017· 58 citedOpen Access
Prospective functional classification of all possible missense variants in PPARG
Nature Genetics·2016· 268 citedOpen Access
The genomic substrate for adaptive radiation in African cichlid fish
2015Open Access
Comprehensive variation discovery in single human genomes
Nature Genetics·2014· 239 citedOpen Access
Comprehensive variation discovery in single human genomes
DSpace@MIT (Massachusetts Institute of Technology)·2014Open Access
The genomic substrate for adaptive radiation in African cichlid fish
Nature·2014· 1.0k citedOpen Access
Assemblathon 2: evaluating <i>de novo</i> methods of genome assembly in three vertebrate species
GigaScience·2013· 723 citedOpen Access
The African coelacanth genome provides insights into tetrapod evolution
Nature·2013· 680 citedOpen Access
Novel origins of copy number variation in the dog genome
Genome biology·2012· 88 citedOpen Access
Finished bacterial genomes from shotgun sequence data
Genome Research·2012· 220 citedOpen Access
Assemblathon 1: A competitive assessment of de novo short read assembly methods
Genome Research·2011· 535 citedOpen Access
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Frequent Co-authors

David B. Jaffe(11), Sante Gnerre(10), Chad Nusbaum(10), Eric S. Lander(10), Iain MacCallum(9), Michael C. Zody(9), Kerstin Lindblad‐Toh(9), Matthew Meyerson(9), Dariusz Przybylski(7), Filipe J. Ribeiro(7), Shuangye Yin(7), Louise Williams(6), Jessica Alföldi(6), David E. Root(6), Sarah Young(5), Evan Mauceli(5), Xiaoping Yang(5), Federica Piccioni(5), Cory M. Johannessen(5), Matthew T. Webster(4)