Gijs R. van den Brink

University of Padua — Italy

Biochemistry, Genetics and Molecular Biology · Life Sciences

102h-index45.1kcitations548works28.62yr avg
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Research Topics

Lipid Membrane Structure and Behavior(63), Inflammatory Bowel Disease(60), Microscopic Colitis(42), Bacterial Genetics and Biotechnology(40), Cancer Cells and Metastasis(37)

Publications540 total

Identification of a lipid oxygen radical defense pathway and its epigenetic control
Nature Communications·2025Open Access
Antxr2-mediated fine-tuning of Collagen VI ensures skeletal muscle function
2025· 1 citedOpen Access
Injury-induced intestinal stem cell renewal requires capillary morphogenesis gene 2
EMBO Molecular Medicine·2025· 2 citedOpen Access
Anthrax toxin receptor 2 is the Receptor for <i>Clostridium perfringens</i> NetF: Structural Insights into Toxin Binding and Pore Formation
2025Open Access
Molecular Regulation and Physiological Role of GOLPH3-mediated Golgi retention
2025· 3 citedOpen Access
Adult-type granulosa cell tumor: towards tailored diagnostics and personalized treatment
2025
Identification of the Lipid Oxygen Radical Defense pathway and its epigenetic control
2025Open Access
Author Reply to Peer Reviews of Injury-Induced Intestinal Stem Cell Renewal Requires Capillary Morphogenesis Gene 2
2025
Identification of a Lipid Oxygen Radical Defense pathway and its epigenetic control
2025Open Access
Intestinal stem cell renewal controlled by capillary morphogenesis gene 2 following injury
2025Open Access
986 ENDOSCOPIC OUTCOMES WITH EARLY TREATMENT IN NEWLYDIAGNOSED CROHN'S DISEASE: EVIDENCE FROM PROFILE, A MULTICENTRE, RANDOMIZED, OPEN-LABEL, BIOMARKER-STRATIFIED CLINICAL TRIAL
Gastroenterology·2024
Abstract 1572: <i>POU5F1B</i> is a human-restricted ROCK inhibitor-sensitive oncoprotein that restructures membrane nanodomains to increase cell adhesion
Cancer Research·2024
A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn's disease (PROFILE): a multicentre, open-label randomised controlled trial
˜The œLancet. Gastroenterology & hepatology·2024· 230 citedOpen Access
Mechanisms and functions of protein S-acylation
Nature Reviews Molecular Cell Biology·2024· 164 citedOpen Access
SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase
Nature Communications·2023· 14 citedOpen Access
The human-restricted oncoprotein POU5F1B enhances cell invasiveness through plasma membrane remodeling
2023Open Access
S‐acylation: an orchestrator of the life cycle and function of membrane proteins
FEBS Journal·2023· 8 citedOpen Access
Refining S-acylation: Structure, regulation, dynamics, and therapeutic implications
The Journal of Cell Biology·2023· 25 citedOpen Access
Grp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis
Life Science Alliance·2023· 8 citedOpen Access
SARS-CoV-2 shifts transcription of host gene to increase Spike acylation and boost infectivity
2023Open Access
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Frequent Co-authors

Laurence Abrami(10), Manon E. Wildenberg(7), James C.H. Hardwick(7), Geert D’Haens(6), Maikel P. Peppelenbosch(6), Daniël W. Hommes(6), Sander J. H. van Deventer(5), Cyriel Y. Ponsioen(4), Matteo Dal Peraro(4), Marjolijn Duijvestein(4), Anne Christine W. Vos(4), Séverine Vermeire(4), Ioan Iacovache(4), Mark Löwenberg(3), Auke P. Verhaar(3), Stephen H. Leppla(3), Robert G. Parton(3), G. Johan A. Offerhaus(3), Liudmila L. Kodach(3), Mirko Bischofberger(3)