Krisztina M. Zsebo

Medicine · Health Sciences

36h-index10.9kcitations60works1.02yr avg
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Research Topics

Cardiac electrophysiology and arrhythmias(11), Viral Infections and Immunology Research(11), Virus-based gene therapy research(7), Mesenchymal stem cell research(6), Pluripotent Stem Cells Research(6)

Publications59 total

Anti-Syndecan 2 Antibody Treatment Reduces Edema Formation and Inflammation of Murine Laser-Induced CNV
Translational Vision Science & Technology·2025· 1 citedOpen Access
JoVE Video Dataset
2022
Multiple Intravenous Bolus Dosing and Invasive Hemodynamic Assessment in a Hypoxia-Induced Mouse Pulmonary Artery Hypertension Model
Journal of Visualized Experiments·2022· 1 cited
Intratracheal Gene Delivery of SERCA2a Ameliorates Chronic Post-Capillary Pulmonary Hypertension
Journal of the American College of Cardiology·2016· 72 citedOpen Access
Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebo-controlled, phase 2b trial
The Lancet·2016· 492 citedOpen Access
Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders
Journal of Biological Chemistry·2015· 190 citedOpen Access
Abstract 14156: Airway Gene Delivery of Serca2a Ameliorates Chronic Pulmonary Hypertension in a Large Animal Preclinical Model
Circulation·2015
CUPID 2: A Phase 2b Trial Investigating the Efficacy and Safety of the Intracoronary Administration of AAV1/SERCA2a in Patients with Advanced Heart Failure
Journal of Cardiac Failure·2015· 9 cited
Abstract 17141: Stem Cell Factor Gene Transfer in a Swine Model of Ischemic Cardiomyopathy is accompanied by decreased apoptosis and proliferating cKit+ cell
Circulation·2014
Stem Cell Factor Gene Transfer Improves Cardiac Function After Myocardial Infarction in Swine
Circulation Heart Failure·2014· 37 citedOpen Access
Stem Cell Factor Gene Transfer Improves Cardiac Function After Myocardial Infarction in Swine
DSpace@MIT (Massachusetts Institute of Technology)·2014Open Access
Design of a Phase 2b Trial of Intracoronary Administration of AAV1/SERCA2a in Patients With Advanced Heart Failure
JACC Heart Failure·2014· 150 cited
Discovery of Enzyme Modulators via High-Throughput Time-Resolved FRET in Living Cells
SLAS DISCOVERY·2014· 107 citedOpen Access
Long-Term Effects of AAV1/SERCA2a Gene Transfer in Patients With Severe Heart Failure
Circulation Research·2013· 302 cited
Therapeutic Efficacy of AAV1.SERCA2a in Monocrotaline-Induced Pulmonary Arterial Hypertension
Circulation·2013· 116 citedOpen Access
Targeting Diabetes with a Novel Small Molecule Activator of Sarco/endoplasmic Reticulum Ca2+‐ATPase (SERCA)
The FASEB Journal·2013
Stem Cell Factor Gene Transfer Promotes Cardiac Repair After Myocardial Infarction via In Situ Recruitment and Expansion of c-kit <sup>+</sup> Cells
Circulation Research·2012· 67 citedOpen Access
High-Throughput FRET Assay Yields Allosteric SERCA Activators
SLAS DISCOVERY·2012· 100 citedOpen Access
Evaluation of the Long-Term Effects of AAV1/SERCA2a Gene Therapy on Clinical Events in Heart Failure Patients Using a Novel Statistical Model: Results and Implications for Future Trials
Journal of Cardiac Failure·2012
Concomitant Intravenous Nitroglycerin With Intracoronary Delivery of AAV1.SERCA2a Enhances Gene Transfer in Porcine Hearts
Molecular Therapy·2012· 41 citedOpen Access
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Frequent Co-authors

Roger J. Hajjar(15), Barry Greenberg(8), Kevin M. Smith(6), Yoshiaki Kawase(6), Keith Langley(5), Hsieng S. Lu(5), Mariell Jessup(5), Brian E. Jaski(5), Alex Yaroshinsky(5), Jette Wypych(4), Ian McNiece(4), J Rudy(4), Djamel Lebeche(4), Lahouaria Hadri(4), Kiyotake Ishikawa(4), Francis H. Martin(3), Stephen J. Galli(3), Thomas C. Boone(3), Yasuhisa Matsui(3), Brigid L.M. Hogan(3)