V. Sasisekharan

Massachusetts Institute of Technology — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

41h-index12.0kcitations150works0.02yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(60), RNA and protein synthesis mechanisms(35), Advanced biosensing and bioanalysis techniques(24), Influenza Virus Research Studies(16), Protein Structure and Dynamics(14)

Publications150 total

A Chiral Pentagonal Polyhedral Framework for Characterizing Virus Capsid Structures
Trends in Microbiology·2017· 11 cited
Glycan–protein interactions in viral pathogenesis
DSpace@MIT (Massachusetts Institute of Technology)·2016· 3 citedOpen Access
Glycan–protein interactions in viral pathogenesis
Current Opinion in Structural Biology·2016· 137 citedOpen Access
Receptor Specificity in Surveillance of Natural Sequence Evolution of Influenza A Virus Hemagglutinin
Caister Academic Press eBooks·2016
Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope
DSpace@MIT (Massachusetts Institute of Technology)·2015· 1 citedOpen Access
Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope
Cell·2015· 138 citedOpen Access
Glycan receptor specificity as a useful tool for characterization and surveillance of influenza A virus
Trends in Microbiology·2014· 29 citedOpen Access
Glycan receptor specificity as a useful tool for characterization and surveillance of influenza A virus
DSpace@MIT (Massachusetts Institute of Technology)·2014· 1 citedOpen Access
Broadly Neutralizing Influenza Hemagglutinin Stem-Specific Antibody CR8020 Targets Residues that Are Prone to Escape due to Host Selection Pressure
DSpace@MIT (Massachusetts Institute of Technology)·2014Open Access
Broadly Neutralizing Influenza Hemagglutinin Stem-Specific Antibody CR8020 Targets Residues that Are Prone to Escape due to Host Selection Pressure
Cell Host & Microbe·2014· 66 citedOpen Access
Glycan Receptor Binding of the Influenza A Virus H7N9 Hemagglutinin
Cell·2013· 136 citedOpen Access
Structural Determinants for Naturally Evolving H5N1 Hemagglutinin to Switch Its Receptor Specificity
Cell·2013· 93 citedOpen Access
Antigenically intact hemagglutinin in circulating avian and swine influenza viruses and potential for H3N2 pandemic
Scientific Reports·2013· 23 citedOpen Access
Redesign of a cross-reactive antibody to dengue virus with broad-spectrum activity and increased in vivo potency
Proceedings of the National Academy of Sciences·2013· 66 citedOpen Access
Networks link antigenic and receptor-binding sites of influenza hemagglutinin: Mechanistic insight into fitter strain propagation
Scientific Reports·2011· 51 citedOpen Access
Networks link antigenic and receptor-binding sites of influenza hemagglutinin: Mechanistic insight into fitter strain propagation
DSpace@MIT (Massachusetts Institute of Technology)·2011Open Access
The many faces of the YopM effector from plague causative bacterium <i>Yersinia pestis</i> and its implications for host immune modulation
Innate Immunity·2010· 29 cited
Glycans as receptors for influenza pathogenesis
Glycoconjugate Journal·2010· 3 citedOpen Access
Atomic Interaction Networks in the Core of Protein Domains and Their Native Folds
PLoS ONE·2010· 41 citedOpen Access
Extrapolating from sequence—the 2009 H1N1 'swine' influenza virus
Nature Biotechnology·2009· 90 cited
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Frequent Co-authors

Ram Sasisekharan(18), Rahul Raman(11), G. N. Ramachandran(8), Kannan Tharakaraman(7), A. V. Lakshminarayanan(7), S. Raguram(6), Ganesh Venkataraman(6), Karthik Viswanathan(5), Venkataramanan Soundararajan(4), Manju Bansal(3), Zachary Shriver(3), Róbert Langer(3), H. Todd Miles(3), P. K. Ponnuswamy(3), C. Ramakrishnan(2), Aarthi Chandrasekaran(2), Aravind Srinivasan(2), Terrence M. Tumpey(2), Steffen Ernst(2), Luke N. Robinson(2)