Kannan Tharakaraman

Massachusetts Institute of Technology — United States

Medicine · Health Sciences

19h-index1.3kcitations43works7.02yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Influenza Virus Research Studies(15), Respiratory viral infections research(11), Monoclonal and Polyclonal Antibodies Research(9), Mosquito-borne diseases and control(7), Genomics and Chromatin Dynamics(7)

Publications43 total

Rapid and Scalable Production of Functional SARS-CoV-2 Virus-like Particles (VLPs) by a Stable HEK293 Cell Pool
Vaccines·2024· 7 citedOpen Access
Enhancing antibody affinity through experimental sampling of non-deleterious CDR mutations predicted by machine learning
Communications Chemistry·2023· 19 citedOpen Access
Machine Learning-Guided Antibody Engineering That Leverages Domain Knowledge To Overcome The Small Data Problem
2023· 6 citedOpen Access
Generation of bispecific antibodies by structure-guided redesign of IgG constant regions
Frontiers in Immunology·2023· 5 citedOpen Access
Optimizing Antibody Affinity and Developability Using a Framework–CDR Shuffling Approach—Application to an Anti-SARS-CoV-2 Antibody
Viruses·2022· 10 citedOpen Access
Prediction of the structural interface between fibroblast growth factor23 and Burosumab using alanine scanning and molecular docking
Scientific Reports·2022· 4 citedOpen Access
Prediction of the structural interface between fibroblast growth factor23 and Burosumab using alanine scanning and molecular docking
Research Square (Research Square)·2022Open Access
Modified recombinant human erythropoietin with potentially reduced immunogenicity
Scientific Reports·2021· 10 citedOpen Access
Orthogonal immunoassays for IgG antibodies to SARS-CoV-2 antigens reveal that immune response lasts beyond 4 mo post illness onset
Proceedings of the National Academy of Sciences·2021· 30 citedOpen Access
Prediction of the binding interface between monoclonal antibody m102.4 and Nipah attachment glycoprotein using structure-guided alanine scanning and computational docking
Scientific Reports·2020· 18 citedOpen Access
Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody 513
Scientific Reports·2018· 21 citedOpen Access
Rational Engineering and Characterization of an mAb that Neutralizes Zika Virus by Targeting a Mutationally Constrained Quaternary Epitope
Cell Host & Microbe·2018· 30 citedOpen Access
Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody 513
DSpace@MIT (Massachusetts Institute of Technology)·2018Open Access
Rational Engineering and Characterization of an mAb that Neutralizes Zika Virus by Targeting a Mutationally Constrained Quaternary Epitope
PMC·2018
An inter-residue network model to identify mutational-constrained regions on the Ebola coat glycoprotein
Scientific Reports·2017· 5 citedOpen Access
An inter-residue network model to identify mutational-constrained regions on the Ebola coat glycoprotein
DSpace@MIT (Massachusetts Institute of Technology)·2017Open Access
A Structural and Mathematical Modeling Analysis of the Likelihood of Antibody-Dependent Enhancement in Influenza
Trends in Microbiology·2016· 17 citedOpen Access
Glycan–protein interactions in viral pathogenesis
DSpace@MIT (Massachusetts Institute of Technology)·2016· 3 citedOpen Access
A Structural and Mathematical Modeling Analysis of the Likelihood of Antibody-Dependent Enhancement in Influenza
DSpace@MIT (Massachusetts Institute of Technology)·2016Open Access
Glycan–protein interactions in viral pathogenesis
Current Opinion in Structural Biology·2016· 137 citedOpen Access
page 1 of 3Next →

Frequent Co-authors

Ram Sasisekharan(33), Rahul Raman(16), V. Sasisekharan(14), Zachary Shriver(11), Vidya Subramanian(10), Akila Jayaraman(9), Karthik Viswanathan(8), John L. Spouge(8), Julien Lescar(6), Leonardo Mariño‐Ramírez(6), Mathuros Ruchirawat(6), Mayuree Fuangthong(6), Gregory J. Babcock(5), David Landsman(5), Kuan Rong Chan(4), Yee Hwa Wong(4), Hwee Cheng Tan(4), Chong Wai Liew(4), Boopathy Ramakrishnan(4), Eng Eong Ooi(4)