Charles P. Taylor

Taylor's University — Malaysia

Neuroscience · Life Sciences

52h-index9.9kcitations104works0.02yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(57), Ion channel regulation and function(34), Pain Mechanisms and Treatments(18), Epilepsy research and treatment(15), Photoreceptor and optogenetics research(12)

Publications104 total

Analgesia with Gabapentin and Pregabalin May Involve N-Methyl-d-Aspartate Receptors, Neurexins, and Thrombospondins
Journal of Pharmacology and Experimental Therapeutics·2020· 52 citedOpen Access
Pharmacology of dextromethorphan: Relevance to dextromethorphan/quinidine (Nuedexta®) clinical use
Pharmacology & Therapeutics·2016· 174 citedOpen Access
The diverse therapeutic actions of pregabalin: is a single mechanism responsible for several pharmacological activities?
Trends in Pharmacological Sciences·2013· 270 cited
Pregabalin is a potent and selective ligand for α2δ-1 and α2δ-2 calcium channel subunits
European Journal of Pharmacology·2011· 147 cited
Anxiolytic-Like Activity of Pregabalin in the Vogel Conflict Test in α2δ-1 (R217A) and α2δ-2 (R279A) Mouse Mutants
Journal of Pharmacology and Experimental Therapeutics·2011· 52 cited
Central Sensitization and CaVα2δ Ligands in Chronic Pain Syndromes: Pathologic Processes and Pharmacologic Effect
Journal of Pain·2010· 73 cited
Reply to: How does gabapentin relieve pain? (Marshall Devor)
Pain·2009· 3 cited
Mechanisms of analgesia by gabapentin and pregabalin – Calcium channel α2-δ [Cavα2-δ] ligands
Pain·2009· 249 cited
Oxadiazolone bioisosteres of pregabalin and gabapentin
Bioorganic & Medicinal Chemistry Letters·2008· 14 cited
Anxiolytic profile of pregabalin on elicited hippocampal theta oscillation
Neuropharmacology·2008· 62 cited
Immunostaining of rat brain, spinal cord, sensory neurons and skeletal muscle for calcium channel alpha2-delta (α2-δ) type 1 protein
Neuroscience·2008· 128 cited
CCDC 665078: Experimental Crystal Structure Determination
The Cambridge Structural Database·2008Open Access
Effect of a New α<sub>2</sub>δ Ligand PD-217014 on Visceral Hypersensitivity Induced by 2,4,6-Trinitrobenzene Sulfonic Acid in Rats
Pharmacology·2007· 23 cited
Ca2+ channel α2δ ligands: novel modulators of neurotransmission
Trends in Pharmacological Sciences·2007· 383 cited
Pharmacology and mechanism of action of pregabalin: The calcium channel α2–δ (alpha2–delta) subunit as a target for antiepileptic drug discovery
Epilepsy Research·2006· 544 cited
Pregabalin action at a model synapse: Binding to presynaptic calcium channel α2-δ subunit reduces neurotransmission in mice
European Journal of Pharmacology·2006· 70 cited
Pregabalin Reduces the Release of Synaptic Vesicles from Cultured Hippocampal Neurons
Molecular Pharmacology·2006· 109 cited
Carboxylate bioisosteres of pregabalin
Bioorganic & Medicinal Chemistry Letters·2006· 16 cited
Calcium channel alpha2-delta type 1 subunit is the major binding protein for pregabalin in neocortex, hippocampus, amygdala, and spinal cord: An ex vivo autoradiographic study in alpha2-delta type 1 genetically modified mice
Brain Research·2006· 153 cited
Activity profile of pregabalin in rodent models of epilepsy and ataxia
Epilepsy Research·2005· 91 cited
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Frequent Co-authors

Mark G. Vartanian(7), Mark L. Weber(7), F. Edward Dudek(6), Devin Welty(3), Sean D. Donevan(3), F. Edward Dudek(3), Robert W. Snow(3), Ti‐Zhi Su(2), David Dooley(2), Andrew Thorpe(2), Jack J. Kinsora(2), Deborah A. Berkich(2), Susan M. Hutson(2), Feng Bian(2), Peter G. Aitken(2), Maryceline T. Espanol(2), P.M. Larkman(2), Peter Lipton(2), George C. Newman(2), Kimberly L. Panizzon(2)