Juan José Cazzulo

National University of General San Martín — Argentina

Medicine · Health Sciences

45h-index6.4kcitations181works0.02yr avg
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Research Topics

Trypanosoma species research and implications(108), Research on Leishmaniasis Studies(48), Biochemical and Molecular Research(43), Enzyme Structure and Function(23), Peptidase Inhibition and Analysis(16)

Publications179 total

Carboxypeptidase Taq-like peptidases from trypanosomatids
Handbook of Proteolytic Enzymes·2025
List of contributors
Handbook of Proteolytic Enzymes·2025
Screening and Identification of Metacaspase Inhibitors: Evaluation of Inhibition Mechanism and Trypanocidal Activity
Antimicrobial Agents and Chemotherapy·2020· 2 citedOpen Access
Update on relevant trypanosome peptidases: Validated targets and future challenges
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics·2020· 25 cited
Design, synthesis, and evaluation of substrate – analogue inhibitors of Trypanosoma cruzi ribose 5-phosphate isomerase type B
Bioorganic & Medicinal Chemistry Letters·2020· 6 cited
Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases
Molecular Cell·2020· 92 citedOpen Access
Potent and selective inhibitors for M32 metallocarboxypeptidases identified from high-throughput screening of anti-kinetoplastid chemical boxes
PLoS neglected tropical diseases·2019· 5 citedOpen Access
Target-based Screening of the Chagas Box: Setting Up Enzymatic Assays to Discover Specific Inhibitors Across Bioactive Compounds
Current Medicinal Chemistry·2019· 3 cited
Simplified inducible system for Trypanosoma brucei
PLoS ONE·2018· 10 citedOpen Access
Author Correction: Novel scaffolds for inhibition of Cruzipain identified from high-throughput screening of anti-kinetoplastid chemical boxes
Scientific Reports·2018· 1 citedOpen Access
<scp>DNA</scp>‐damage inducible protein 1 is a conserved metacaspase substrate that is cleaved and further destabilized in yeast under specific metabolic conditions
FEBS Journal·2018· 12 citedOpen Access
Substrate specificity profiling of M32 metallocarboxypeptidases from Trypanosoma cruzi and Trypanosoma brucei
Molecular and Biochemical Parasitology·2017· 8 cited
Novel scaffolds for inhibition of Cruzipain identified from high-throughput screening of anti-kinetoplastid chemical boxes
Scientific Reports·2017· 35 citedOpen Access
Structure, kinetic characterization and subcellular localization of the two ribulose 5-phosphate epimerase isoenzymes from Trypanosoma cruzi
PLoS ONE·2017· 10 citedOpen Access
Data from: Different proteomic strategies to identify genuine SUMO targets and their modification sites in Trypanosoma brucei procyclic forms
Figshare·2016· 1 citedOpen Access
Biosynthesis of SUMOylated Proteins in Bacteria Using the Trypanosoma brucei Enzymatic System
PLoS ONE·2015· 10 citedOpen Access
Different proteomic strategies to identify genuine Small Ubiquitin-like MOdifier targets and their modification sites in<i>T</i><i>rypanosoma brucei</i>procyclic forms
Cellular Microbiology·2015· 18 citedOpen Access
Antiparasitic effect of a fraction enriched in tight-binding protease inhibitors isolated from the Caribbean coral Plexaura homomalla
Experimental Parasitology·2013· 17 citedOpen Access
Metacaspases, Autophagins and Metallocarboxypeptidases: Potential New Targets for Chemotherapy of the Trypanosomiases
Current Medicinal Chemistry·2013· 14 citedOpen Access
Drug Targets in Trypanosomal and Leishmanial Pentose Phosphate Pathway
2013· 12 citedOpen Access
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Frequent Co-authors

Alberto C.C. Frasch(6), Joaquı́n J.B. Cannata(6), Oscar Campetella(5), Vanina E. Álvarez(5), Javier Martı̂nez(4), Vito Türk(4), Dante Maugeri(4), Michael P. Barrett(3), Berta M. Franke de Cazzulo(3), Daniel O. Sánchez(3), Carlos A. Labriola(3), Armando J. Parodi(3), A.O.M. Stoppani(3), T. K. Sundaram(3), H.L. Kornberg(3), Agustina Chidichimo(3), Richard Burchmore(2), Juan C. Engel(2), Wanderley de Souza(2), Gregor Kosec(2)