R L Martuza

Harvard University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index1.5kcitations16works0.02yr avg
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Research Topics

Virus-based gene therapy research(12), Herpesvirus Infections and Treatments(8), Viral Infectious Diseases and Gene Expression in Insects(4), RNA Interference and Gene Delivery(3), Sarcoma Diagnosis and Treatment(2)

Publications16 total

ET-17 * TRANSIENT FASTING ENHANCES REPLICATION AND THERAPEUTIC ACTIVITY OF ONCOLYTIC HSV IN GLIOBLASTOMA THERAPY
Neuro-Oncology·2014Open Access
Combination of vinblastine and oncolytic herpes simplex virus vector expressing IL-12 therapy increases antitumor and antiangiogenic effects in prostate cancer models
Cancer Gene Therapy·2012· 51 citedOpen Access
Biological purging of breast cancer cells using an attenuated replication-competent herpes simplex virus in human hematopoietic stem cell transplantation.
PubMed·2001· 28 cited
Combination suicide/cytokine gene therapy as adjuvants to a defective herpes simplex virus-based cancer vaccine
Gene Therapy·2001· 43 cited
In situ expression of soluble B7-1 in the context of oncolytic herpes simplex virus induces potent antitumor immunity.
PubMed·2001· 89 cited
Effect of prior exposure to herpes simplex virus 1 on viral vector-mediated tumor therapy in immunocompetent mice
Gene Therapy·1999· 98 cited
Transcriptional targeting of herpes simplex virus for cell-specific replication
Journal of Virology·1997· 106 citedOpen Access
Treatment of human malignant meningiomas by G207, a replication-competent multimutated herpes simplex virus 1.
PubMed·1995· 145 cited
Treatment of glioma by engineered interleukin 4-secreting cells.
PubMed·1993· 152 cited
Gene therapy of maliganant brain tumors: A rat glioma line bearing the herpes simplex virus type 1‐thymidine kinase gene and wild type retrovirus kills other tumor cells
Journal of Neuroscience Research·1992· 168 cited
Experimental therapy of human glioma by means of a genetically engineered virus mutant
The Society for Neuroscience Abstracts·1991· 2 cited
Gene delivery to glioma cells in rat brain by grafting of a retrovirus packaging cell line
Journal of Neuroscience Research·1990· 194 cited
Equal parental origin of chromosome 22 losses in human sporadic meningioma: no evidence for genomic imprinting.
PubMed·1990· 11 cited
Sarcomatous proliferation of the vasculature in a subependymoma
Acta Neuropathologica·1989· 19 cited
Linkage analysis in von Recklinghausen neurofibromatosis (NF1) with DNA markers for chromosome 17
Genomics·1987· 26 cited
Genetic linkage of von Recklinghausen neurofibromatosis to the nerve growth factor receptor gene
Cell·1987· 370 citedOpen Access

Frequent Co-authors

Samuel D. Rabkin(8), Bernd R. Seizinger(3), Guy A. Rouleau(3), X. O. Breakefield(3), James F. Gusella(3), Laurie J. Ozelius(2), AH Lane(2), A.G. Faryniarz(2), Moses V. Chao(2), Bruce R. Korf(2), Dilys M. Parry(2), Wendy Hobbs(2), J.A. Iannazzi(2), Jennie C. L. Roy(2), J.L. Bader(2), M. Anne Spence(2), Allen D. Roses(2), M. Priscilla Short(2), Amy Malick(2), Tomoki Todo(2)