Isabelle Crevel

St George's, University of London — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index1.2kcitations21works4.02yr avg
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Research Topics

Microtubule and mitosis dynamics(11), Cancer therapeutics and mechanisms(6), DNA and Nucleic Acid Chemistry(5), Cellular transport and secretion(4), DNA Repair Mechanisms(3)

Publications21 total

Supernumerary proteins of the human mitochondrial ribosomal small subunit are integral for assembly and translation
iScience·2024· 4 citedOpen Access
Supernumerary proteins of the human mitochondrial ribosomal small subunit are integral for assembly and translation
2022· 2 citedOpen Access
Studies of prokaryotic Type II topoisomerase drug inhibition
Acta Crystallographica Section A Foundations and Advances·2017· 1 citedOpen Access
Quinolone(Moxifloxacin)-DNA cleavage complex of gyrase from S. pneumoniae
2015· 3 cited
Type II topoisomerases as targets for rational drug design
Acta Crystallographica Section A Foundations and Advances·2014Open Access
Insights into the mechanism for DNA capture and transport by topoisomerase II provided by the high-resolution structure of an 'open' topoisomerase II-DNA complex
Acta Crystallographica Section A Foundations of Crystallography·2013· 1 citedOpen Access
Structure of an ‘open’ clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport
Nucleic Acids Research·2013· 66 citedOpen Access
A three-gate structure of topoisomerase IV from Streptococcus pneumoniae
2012
Drosophila RecQ4 Is Directly Involved in Both DNA Replication and the Response to UV Damage in S2 Cells
PLoS ONE·2012· 13 citedOpen Access
Decreased MCM2-6 in Drosophila S2 Cells Does Not Generate Significant DNA Damage or Cause a Marked Increase in Sensitivity to Replication Interference
PLoS ONE·2011· 10 citedOpen Access
Single‐headed mode of kinesin‐5
EMBO Reports·2008· 26 citedOpen Access
S-Trityl-L-cysteine Is a Reversible, Tight Binding Inhibitor of the Human Kinesin Eg5 That Specifically Blocks Mitotic Progression
Journal of Biological Chemistry·2006· 281 citedOpen Access
What kinesin does at roadblocks: the coordination mechanism for molecular walking
The EMBO Journal·2003· 89 citedOpen Access
M Phase Phosphoprotein 1 Is a Human Plus-end-directed Kinesin-related Protein Required for Cytokinesis
Journal of Biological Chemistry·2003· 99 citedOpen Access
Interaction of the Mitotic Inhibitor Monastrol with Human Kinesin Eg5
Biochemistry·2002· 179 cited
KIF1D is a fast non-processive kinesin that demonstrates novel K-loop-dependent mechanochemistry
The EMBO Journal·2001· 78 citedOpen Access
The conformational cycle of kinesin
Philosophical Transactions of the Royal Society B Biological Sciences·2000· 39 citedOpen Access
Coupled chemical and mechanical reaction steps in a processive Neurospora kinesin
The EMBO Journal·1999· 70 citedOpen Access
Weak and Strong States of Kinesin and ncd
Journal of Molecular Biology·1996· 151 cited
Kinesin and ncd Bind Through a Single Head to Microtubules and Compete for a Shared MT Binding Site
Journal of Molecular Biology·1995· 73 cited
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Frequent Co-authors

Robert A. Cross(8), Ivan Laponogov(6), Dennis A. Veselkov(6), Xiao-Su Pan(6), L. Mark Fisher(6), Mark R. Sanderson(6), Dimitrios A. Skoufias(2), Salvatore DeBonis(2), Luc Lebeau(2), Richard H. Wade(2), David D. Hackney(2), Frank Kozielski(2), Andrew Lockhart(2), María C. Alonso(2), Stefan Weiß(2), Michael A. Geeves(2), Keiko Hirose(2), Gilles Crevel(2), Sue Cotterill(2), Taru Hilander(2)