Don R. Phillips

La Trobe University — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

39h-index5.6kcitations162works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

DNA and Nucleic Acid Chemistry(63), Cancer therapeutics and mechanisms(51), DNA Repair Mechanisms(22), Synthesis and Biological Evaluation(22), Metal complexes synthesis and properties(21)

Publications162 total

An evaluation of the interaction of pixantrone with formaldehyde-releasing drugs in cancer cells
Cancer Chemotherapy and Pharmacology·2022· 2 cited
Abstract 992: A switch in mechanism of action attenuates doxorubicin-mediated cardiotoxicity
Cancer Research·2021
Development of an automated assay for accelerated in vitro detection of DNA adduct-inducing and crosslinking agents
Bioorganic & Medicinal Chemistry Letters·2021· 2 cited
A switch in mechanism of action attenuates doxorubicin-mediated cardiotoxicity.
Cancer Research·2021
Understanding mass spectrometry images: complexity to clarity with machine learning
Biopolymers·2020· 26 citedOpen Access
Formaldehyde-activated WEHI-150 induces DNA interstrand crosslinks with unique structural features
Bioorganic & Medicinal Chemistry·2019· 4 cited
Building a New Rail System
Indiana University Press eBooks·2018
Encapsulation of Mitoxantrone within Cucurbit[8]uril Decreases Toxicity and Enhances Survival in a Mouse Model of Cancer
ACS Medicinal Chemistry Letters·2017· 35 cited
Factors determining the stability, size distribution, and cellular accumulation of small, monodisperse chitosan nanoparticles as candidate vectors for anticancer drug delivery: application to the passive encapsulation of [<sup>14</sup>C]-doxorubicin [Corrigendum]
Nanotechnology Science and Applications·2016· 10 citedOpen Access
Reversible and formaldehyde-mediated covalent binding of a bis-amino mitoxantrone analogue to DNA
Organic & Biomolecular Chemistry·2016· 7 cited
Isolation and structural analysis of the covalent adduct formed between a bis-amino mitoxantrone analogue and DNA: a pathway to major–minor groove cross-linked adducts
Organic & Biomolecular Chemistry·2016· 4 citedOpen Access
Factors determining the stability, size distribution, and cellular accumulation of small, monodisperse chitosan nanoparticles as candidate vectors for anticancer drug delivery: application to the passive encapsulation of [14C]-doxorubicin
Nanotechnology Science and Applications·2015· 330 citedOpen Access
Mitoxantrone, More than Just Another Topoisomerase II Poison
Medicinal Research Reviews·2015· 231 cited
Potential Therapeutic Advantages of Doxorubicin when Activated by Formaldehyde to Function as a DNA Adduct-Forming Agent
Current Topics in Medicinal Chemistry·2015· 20 cited
Binding of pixantrone to DNA at CpA dinucleotide sequences and bulge structures
Organic & Biomolecular Chemistry·2015· 5 cited
Design, synthesis, and DNA sequence selectivity of formaldehyde-mediated DNA-adducts of the novel N-(4-aminobutyl) acridine-4-carboxamide
Bioorganic & Medicinal Chemistry Letters·2014· 5 cited
A novel valproic acid prodrug as an anticancer agent that enhances doxorubicin anticancer activity and protects normal cells against its toxicity in vitro and in vivo
Biochemical Pharmacology·2014· 19 cited
The hydroxyl epimer of doxorubicin controls the rate of formation of cytotoxic anthracycline-DNA adducts
Cancer Chemotherapy and Pharmacology·2012· 9 cited
Activation of DNA damage response pathways as a consequence of anthracycline-DNA adduct formation
Biochemical Pharmacology·2012· 70 cited
Disparate Impact of Butyroyloxymethyl Diethylphosphate (AN-7), a Histone Deacetylase Inhibitor, and Doxorubicin in Mice Bearing a Mammary Tumor
PLoS ONE·2012· 24 citedOpen Access
page 1 of 9Next →

Frequent Co-authors

Suzanne M. Cutts(22), Ada Rephaeli(12), Abraham Nudelman(12), Carleen Cullinane(6), Lonnie P. Swift(5), Robin J. White(5), Nataly Tarasenko(4), Benny J. Evison(3), Andrew H. Kaye(3), J. A. REISS(3), Paul J. Pigram(2), Donald M. Crothers(2), Jean LeRiche(2), Kathryn W. Woodburn(2), Nicholas J. Vardaxis(2), John S. Hill(2), James R. Woodward(2), Geoffrey B. Fincher(2), Ken‐ichi Kimura(2), Belinda S. Parker(2)