R G Roeder

Rockefeller University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

39h-index20.4kcitations56works1.52yr avg
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Research Topics

Genomics and Chromatin Dynamics(26), RNA and protein synthesis mechanisms(16), RNA Research and Splicing(16), Epigenetics and DNA Methylation(9), RNA modifications and cancer(8)

Publications56 total

H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbations
Molecular Cell·2025Open Access
JMJD1C forms condensate to facilitate a RUNX1-dependent gene expression program shared by multiple types of AML cells
Protein & Cell·2024· 3 citedOpen Access
A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor γ Binding Properties and Biological Activities
Journal of Medicinal Chemistry·2020· 11 citedOpen Access
RNA Pol II(G)
2018
Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters
Molecular Cell·2016· 265 citedOpen Access
Transcription of cloned Xenopus 5S RNA genes by X. laevis RNA polymerase III in reconstituted systems (recombinant DNA/cell-free extracts/soluble factor/RNA nucleotidyltransferase)
2016
AF10 Regulates Progressive H3K79 Methylation and HOX Gene Expression in Diverse AML Subtypes
Cancer Cell·2014· 181 citedOpen Access
H3K4me3 Interactions with TAF3 Regulate Preinitiation Complex Assembly and Selective Gene Activation
Cell·2013· 465 citedOpen Access
The Mediator subunit MED1/TRAP220 is required for optimal glucocorticoid receptor-mediated transcription activation
Nucleic Acids Research·2007· 52 citedOpen Access
mAM Facilitates Conversion by ESET of Dimethyl to Trimethyl Lysine 9 of Histone H3 to Cause Transcriptional Repression
Molecular Cell·2003· 321 citedOpen Access
Involvement of the TRAP220 Component of the TRAP/SMCC Coactivator Complex in Embryonic Development and Thyroid Hormone Action
Molecular Cell·2000· 290 citedOpen Access
The USA-Derived Transcriptional Coactivator PC2 Is a Submodule of TRAP/SMCC and Acts Synergistically with Other PCs
Molecular Cell·2000· 121 citedOpen Access
TIP30 has an intrinsic kinase activity required for up-regulation of a subset of apoptotic genes
The EMBO Journal·2000· 96 citedOpen Access
DNA Topoisomerase I and PC4 Can Interact with Human TFIIIC to Promote Both Accurate Termination and Transcription Reinitiation by RNA Polymerase III
Molecular Cell·1998· 93 citedOpen Access
Functional significance of the TATA element major groove in transcription initiation by RNA polymerase II
Nucleic Acids Research·1997· 9 citedOpen Access
Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain
Cell·1997· 2.5k citedOpen Access
Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation.
Genes & Development·1997· 155 citedOpen Access
Activator-dependent transcription by mammalian RNA polymerase II: In vitro reconstitution with general transcription factors and cofactors
Methods in enzymology on CD-ROM/Methods in enzymology·1996· 66 cited
Structure and function of a human transcription factor TFIIIB subunit that is evolutionarily conserved and contains both TFIIB- and high-mobility-group protein 2-related domains.
Proceedings of the National Academy of Sciences·1995· 120 citedOpen Access
Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription.
Proceedings of the National Academy of Sciences·1995· 72 citedOpen Access
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Frequent Co-authors

Masami Horikoshi(5), Virgil E. F. Sklar(4), M Horikoshi(4), Judith A. Jaehning(4), D K Lee(3), Jeff DeJong(3), Tetsuro Kokubo(3), Y. Nakatani(3), Wei Gu(2), Zhanyun Tang(2), Hazel Sive(2), Masami Horikoshi(2), Z Wang(2), Tohru Yamamoto(2), P. Anthony Weil(2), Yoshihiro Nakatani(2), Shigeru Hashimoto(2), Alexander Hoffmann(2), Tae Kook Kim(2), N Heintz(2)