Sharad S. Deshpande

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index1.0kcitations48works0.02yr avg
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Research Topics

Ion channel regulation and function(14), Botulinum Toxin and Related Neurological Disorders(14), Neurological disorders and treatments(13), Pesticide Exposure and Toxicity(9), Cholinesterase and Neurodegenerative Diseases(8)

Publications48 total

G. R. Malkani
2017
Small molecule metalloprotease inhibitor with in vitro, ex vivo and in vivo efficacy against botulinum neurotoxin serotype A
Toxicon·2017· 11 citedOpen Access
Cotrimoxazole and neonatal kernicterus: a review
Drug and Chemical Toxicology·2013· 51 citedOpen Access
Effects of enzymatically inactive recombinant botulinum neurotoxin type A at the mouse neuromuscular junctions
Toxicon·2013· 21 citedOpen Access
Reversal of BoNT/A-mediated inhibition of muscle paralysis by 3,4-diaminopyridine and roscovitine in mouse phrenic nerve-hemidiaphragm preparations
Neurochemistry International·2012· 15 cited
Role of Acetylcholinesterase on the Structure and Function of Cholinergic Synapses: Insights Gained from Studies on Knockout Mice
Cellular and Molecular Neurobiology·2011· 18 citedOpen Access
Protection by pyridostigmine bromide of marmoset hemi-diaphragm acetylcholinesterase activity after soman exposure
Chemico-Biological Interactions·2010· 22 cited
Simultaneous or sequential administration of botulinum neurotoxin E does not reduce the duration of paralysis caused by botulinum neurotoxin A in rat EDL muscle
The Botulinum J·2010· 2 cited
Electrophysiological and Ultrastructural Characterization of Neuromuscular Junctions in Diaphragm Muscle of Acetylcholinesterase Knockout Mice
2008
Mechanism of Action of Botulinum Neurotoxin and Overview of Medical Countermeasures for Intoxication
2007
(19) Inhibition of guinea pig hemi-diaphragm acetylcholinesterase activity by pyridostigmine bromide and protection against soman toxicity
Chemico-Biological Interactions·2005· 17 cited
Cytotoxic actions of palytoxin on aortic smooth muscle cells in culture
Journal of Applied Toxicology·2005· 25 cited
Reduced acetylcholine receptor density, morphological remodeling, and butyrylcholinesterase activity can sustain muscle function in acetylcholinesterase knockout mice
Muscle & Nerve·2004· 57 cited
Genetic and immunological comparison of anti-botulinum type A antibodies from immune and non-immune human phage libraries
Vaccine·2002· 96 cited
Neuromuscular Transmission and Muscle Contractility in SNAP-25-deficient Coloboma Mice
NeuroToxicology·2001· 4 cited
Antagonism of botulinum toxin A-mediated muscle paralysis by 3,4-diaminopyridine delivered via osmotic minipumps
Toxicon·2000· 37 cited
Comparison of <i>in vivo</i> and <i>in vitro</i> mouse bioassays for botulinum toxin antagonists
Journal of Applied Toxicology·1999· 4 cited
Comparison of in vivo and in vitro mouse bioassays for botulinum toxin antagonists
Journal of Applied Toxicology·1999· 16 cited
Mechanism of action of sodium cyanide on rat diaphragm muscle
Journal of Applied Toxicology·1999· 11 cited
Mechanism of action of sodium cyanide on rat diaphragm muscle
Journal of Applied Toxicology·1999
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Frequent Co-authors

Michael Adler(18), Edson X. Albuquerque(16), Robert E. Sheridan(10), Frank J. Lebeda(6), Lloyd Guth(4), James P. Apland(4), Theresa J. Smith(3), Tracey A. Hamilton(3), George A. Oyler(3), Oksana Lockridge(3), Ellen G. Duysen(3), Margaret G. Filbert(3), Donald M. Maxwell(3), Charles P. Barrett(2), Edward J. Donati(2), Jordan E. Warnick(2), Angela L. Purcell(2), Baskaran Thyagarajan(2), Julian R. Haigh(2), Richard K. Gordon(2)