Ramesh A. Bhat

Pfizer (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index2.9kcitations44works0.02yr avg

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Research Topics

Wnt/β-catenin signaling in development and cancer(16), Cancer-related gene regulation(16), Virus-based gene therapy research(9), Estrogen and related hormone effects(8), Hepatitis C virus research(6)

Publications44 total

63 cited

Journal of Molecular Endocrinology·2012· 63 citedOpen Access

Regulation of Osteoblast Differentiation and Bone Cancers by Wnt and PTH Signaling Pathways

2 cited

Elsevier eBooks·2010· 2 cited

List of Contributors

Elsevier eBooks·2010

Wnt3‐frizzled 1 chimera as a model to study canonical Wnt signaling

9 cited

Journal of Cellular Biochemistry·2009· 9 cited

Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides: Part II

25 cited

Bioorganic & Medicinal Chemistry·2009· 25 citedOpen Access

Identification of iminooxothiazolidines as secreted frizzled related protein-1 inhibitors

12 cited

Bioorganic & Medicinal Chemistry Letters·2009· 12 citedOpen Access

A cell‐based Dkk1 binding assay reveals roles for extracellular domains of LRP5 in Dkk1 interaction and highlights differences between wild‐type and the high bone mass mutant LRP5(G171V)

12 cited

Journal of Cellular Biochemistry·2009· 12 cited

A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation

124 cited

Bone·2009· 124 cited

Parathyroid hormone synergizes with non‐cyclic AMP pathways to activate the cyclic AMP response element

3 cited

Journal of Cellular Biochemistry·2009· 3 cited

Molecular characterization of induced mutants in groundnut using random amplified polymorphic DNA markers.

3 cited

Journal of Farm Sciences·2009· 3 citedOpen Access

Modulation of Wnt Signaling Through Inhibition of Secreted Frizzled-Related Protein I (sFRP-1) with N-Substituted Piperidinyl Diphenylsulfonyl Sulfonamides

55 cited

Journal of Medicinal Chemistry·2008· 55 citedOpen Access

Immortalized mouse articular cartilage cell lines retain chondrocyte phenotype and respond to both anabolic factor BMP‐2 and pro‐inflammatory factor IL‐1

21 cited

Journal of Cellular Physiology·2007· 21 cited

Regulation of Secreted Frizzled-related Protein-1 by Heparin

41 cited

Journal of Biological Chemistry·2007· 41 citedOpen Access

Structure–Function analysis of secreted frizzled‐related protein‐1 for its Wnt antagonist function

69 cited

Journal of Cellular Biochemistry·2007· 69 cited

Cell‐type Specific Regulation of Recombinant Secreted Frizzled Related‐1 Production by Heparin and Fibroblast Growth Factor

The FASEB Journal·2007

Structure-based mutation analysis shows the importance of LRP5 β-propeller 1 in modulating Dkk1-mediated inhibition of Wnt signaling

48 cited

Gene·2006· 48 cited

The Orphan Receptor Tyrosine Kinase Ror2 Promotes Osteoblast Differentiation and Enhances ex Vivo Bone Formation

76 cited

Molecular Endocrinology·2006· 76 citedOpen Access

Immortalized cell lines from mouse xiphisternum preserve chondrocyte phenotype

6 cited

Journal of Cellular Physiology·2006· 6 cited

The Role of Wnt Signaling in Bone and Mineral Metabolism

9 cited

Clinical Reviews in Bone and Mineral Metabolism·2006· 9 cited

The Wnt antagonist secreted frizzled‐related protein‐1 controls osteoblast and osteocyte apoptosis

165 cited

Journal of Cellular Biochemistry·2005· 165 citedOpen Access

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Frequent Co-authors

Peter V.N. Bodine(18), Barry S. Komm(11), Bheem M. Bhat(10), Barbara Stauffer(8), Julia Billiard(7), Heather A. Harris(5), Shoichi Fukayama(5), Michael D. Lubeck(5), Robert A. Moran(4), Annamarie Mangine(4), Eugene J. Trybulski(4), Girija Krishnamurthy(4), Alan R. Davis(4), Satoshi Mizutani(4), Paul P. Hung(4), B. Thimmappaya(4), Frederick J. Bex(4), Richard J. Murrills(4), Jane B. Lian(3), Mark Stahl(3)