J L Goldstein

Medicine · Health Sciences

47h-index12.4kcitations72works0.02yr avg
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Research Topics

Lipoproteins and Cardiovascular Health(21), Cholesterol and Lipid Metabolism(20), Cancer, Lipids, and Metabolism(20), RNA and protein synthesis mechanisms(7), Lipid metabolism and biosynthesis(7)

Publications71 total

The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins.
UNC Libraries·2020· 22 citedOpen Access
LO73: The state of the evidence for emergency medical services care of adult patients with sepsis: an analysis of appraised research from the Prehospital Evidence-Based Practice (PEP) program
Canadian Journal of Emergency Medicine·2019
P016: Evaluating the impact of a novel mobile care team (MCT) on the prevalence of ambulatory care sensitive conditions presenting to emergency medical services in Nova Scotia
Canadian Journal of Emergency Medicine·2016· 5 citedOpen Access
EFFECTS OF CONCOMITANT ASPIRIN (81 MG QD) ON INCIDENCE OF GASTRIC AND/OR DUODENAL ULCERS IN HEALTHY SUBJECTS TAKING CELECOXIB OR NAPROXEN: A RANDOMIZED, PLACEBO-CONTROLLED TRIAL
JCR Journal of Clinical Rheumatology·2006· 8 cited
1SY01-4 Activators or inhibitors of SREBPs for the treatment of hypercholesterolemia
Atherosclerosis Supplements·2003
Effect of high-energy neutron flux on fiber optics in an active diagnostic on TFTRa)
Review of Scientific Instruments·1995· 19 cited
Effect of high-energy neutron flux on fiber optics in an active diagnostic on TFTR (abstract)a)
Review of Scientific Instruments·1995· 1 cited
Geranylgeranylated Rab proteins terminating in Cys-Ala-Cys, but not Cys-Cys, are carboxyl-methylated by bovine brain membranes in vitro.
Proceedings of the National Academy of Sciences·1994· 60 citedOpen Access
Sterol-resistant transcription in CHO cells caused by gene rearrangement that truncates SREBP-2.
Genes & Development·1994· 104 citedOpen Access
The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins.
Proceedings of the National Academy of Sciences·1994· 422 citedOpen Access
The esophageal mucosal resistance: structure and function of an unique gastrointestinal epithelial barrier.
PubMed·1994· 16 cited
Replacement of serine-871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis induced by ATP depletion.
Proceedings of the National Academy of Sciences·1993· 166 citedOpen Access
The ldl receptor supergene family
1992
The genetic basis of hypercholesterolemia: clinical and therapeutic implications.
PubMed·1992
Translocation of oxysterol binding protein to Golgi apparatus triggered by ligand binding.
The Journal of Cell Biology·1992· 298 citedOpen Access
39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.
Journal of Biological Chemistry·1991· 583 citedOpen Access
The ldl receptors locus in familial hypercholesterolemia mutational analysis of a membrane protein
1990
NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.
Journal of Biological Chemistry·1990· 942 citedOpen Access
Identification of nucleotides responsible for enhancer activity of sterol regulatory element in low density lipoprotein receptor gene.
Journal of Biological Chemistry·1990· 231 citedOpen Access
Different combinations of cysteine-rich repeats mediate binding of low density lipoprotein receptor to two different proteins
Journal of Biological Chemistry·1989· 312 citedOpen Access
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Frequent Co-authors

M S Brown(18), Michael S. Brown(13), Y K Ho(11), Matthew S. Brown(7), Mark S. Brown(5), R G Anderson(4), David W. Bilheimer(4), S K Basu(3), Gregorio Gil(3), J R Faust(3), Jeffrey R. Smith(3), Timothy F. Osborne(3), Wolfgang J. Schneider(3), Joachim Herz(2), Monty Krieger(2), T L Innerarity(2), Robert W. Mahley(2), Phạm T.T.(2), David W. Russell(2), S. Basu(2)