Thomas C. Hohman

Neurotech (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index1.9kcitations45works7.02yr avg
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Research Topics

Aldose Reductase and Taurine(18), Retinal Diseases and Treatments(11), Prenatal Substance Exposure Effects(9), Pain Mechanisms and Treatments(7), Cannabis and Cannabinoid Research(6)

Publications45 total

Cell-Based Ciliary Neurotrophic Factor Therapy for Macular Telangiectasia Type 2
NEJM Evidence·2025· 7 cited
Primate model of chronic retinal neovascularization and vascular leakage
Experimental Eye Research·2020· 11 citedOpen Access
Functional Characterization of Abicipar-Pegol, an Anti-VEGF DARPin Therapeutic That Potently Inhibits Angiogenesis and Vascular Permeability
Investigative Ophthalmology & Visual Science·2018· 72 citedOpen Access
Double-Masked, Randomized, Phase 2 Evaluation of Abicipar Pegol (an Anti-VEGF DARPin Therapeutic) in Neovascular Age-Related Macular Degeneration.
Bern Open Repository and Information System (University of Bern)·2018Open Access
Double-Masked, Randomized, Phase 2 Evaluation of Abicipar Pegol (an Anti-VEGF DARPin Therapeutic) in Neovascular Age-Related Macular Degeneration
Journal of Ocular Pharmacology and Therapeutics·2018· 74 citedOpen Access
In Vitro and In Vivo Characterization of Abicipar Pegol, an anti-VEGF DARPin® Therapeutic
2018
Optimized Dual Protein/miRNA Method to Quantitate Clinical Biomarkers of Ocular Disease
2017
Optimized Method for Protein Quantitation in Ocular Matrices to Support Target Engagement
2016
Hereditary Retinal Dystrophy
Handbook of experimental pharmacology·2016· 51 cited
Reticular Drusen Associated with Geographic Atrophy in Age-Related Macular Degeneration
Investigative Ophthalmology & Visual Science·2011· 177 citedOpen Access
Optical Coherence Tomography and Autofluorescence Findings in Areas with Geographic Atrophy Due to Age-Related Macular Degeneration
Investigative Ophthalmology & Visual Science·2010· 102 cited
Comparison of the effects of an aldose reductase inhibitor and a sorbitol dehydrogenase inhibitor on nerve function in streptozotocin-diabetic rat
Experimental and Clinical Endocrinology & Diabetes·2009· 1 cited
OPPORTUNITIES AND CHALLENGES IN THE DEVELOPMENT OF COMBINATION THERAPY FOR THE TREATMENT OF RETINAL DISEASES
Retina·2009
Drug Intervention Can Correct Subnormal Retinal Oxygenation Response in Experimental Diabetic Retinopathy
Investigative Ophthalmology & Visual Science·2005· 24 cited
Minalrestat, an Aldose Reductase Inhibitor, Corrects the Impaired Microvascular Reactivity in Diabetes
Journal of Pharmacology and Experimental Therapeutics·2003· 31 cited
Streptozotocin-Induced Diabetes Causes Metabolic Changes and Alterations in Neurotrophin Content and Retrograde Transport in the Cervical Vagus Nerve
Experimental Neurology·2001· 57 cited
ATP-sensitive K+ channel effects on nerve function, Na+, K+ ATPase, and glutathione in diabetic rats
European Journal of Pharmacology·2000· 34 cited
Molecular mechanism(s) of insulin action on the expression of the angiotensinogen gene in kidney proximal tubular cells
Journal of the Renin-Angiotensin-Aldosterone System·2000· 9 citedOpen Access
Retinal Capillary Dilation: Early Diabetic-Like Retinopathy in the Galactose-Fed Rat Model
Journal of Ocular Pharmacology and Therapeutics·2000· 7 cited
Influence of tolrestat on the defective leukocyte–endothelial interaction in experimental diabetes
European Journal of Pharmacology·2000· 28 cited
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Frequent Co-authors

Deborah Carper(7), Chihiro Nishimura(4), W. Gerald Robison(4), Norman E. Cameron(4), Lori‐Ann Christie(3), Masayuki Kaneko(3), M. A. Cotter(3), Michael S. Malamas(3), Michael Basso(3), Jane Millen(2), Sarmila DasGupta(2), Steffen Schmitz-Valckenberg(2), Glenn J. Jaffe(2), Monika Fleckenstein(2), Frank G. Holz(2), János G. Filep(2), John S.D. Chan(2), David Callanan(2), Derek Kunimoto(2), Raj K. Maturi(2)