Zong-Yi Li

University of Washington — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index2.4kcitations23works0.02yr avg
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Research Topics

Virus-based gene therapy research(21), CAR-T cell therapy research(11), Viral Infectious Diseases and Gene Expression in Insects(10), Viral gastroenteritis research and epidemiology(7), Immunotherapy and Immune Responses(3)

Publications23 total

Immuno-Therapy with Anti-CTLA4 Antibodies in Tolerized and Non-Tolerized Mouse Tumor Models
PLoS ONE·2011· 17 citedOpen Access
Multimerization of Adenovirus Serotype 3 Fiber Knob Domains Is Required for Efficient Binding of Virus to Desmoglein 2 and Subsequent Opening of Epithelial Junctions
Journal of Virology·2011· 93 citedOpen Access
Desmoglein 2 is a receptor for adenovirus serotypes 3, 7, 11 and 14
Nature Medicine·2010· 427 citedOpen Access
A recombinant adenovirus type 35 fiber knob protein sensitizes lymphoma cells to rituximab therapy
Blood·2009· 28 cited
In situ adenovirus vaccination engages T effector cells against cancer
Vaccine·2009· 55 citedOpen Access
In Vitro and In Vivo Properties of Adenovirus Vectors with Increased Affinity to CD46
Journal of Virology·2008· 66 citedOpen Access
Biodistribution and Safety Profile of Recombinant Adeno-Associated Virus Serotype 6 Vectors following Intravenous Delivery
Journal of Virology·2008· 23 citedOpen Access
Comparison of Adenoviruses From Species B, C, E, and F After Intravenous Delivery
Molecular Therapy·2007· 61 citedOpen Access
Combination of Tumor Site–Located CTL-Associated Antigen-4 Blockade and Systemic Regulatory T-Cell Depletion Induces Tumor-Destructive Immune Responses
Cancer Research·2007· 90 cited
Adenovirus-Platelet Interaction in Blood Causes Virus Sequestration to the Reticuloendothelial System of the Liver
Journal of Virology·2007· 172 citedOpen Access
Evaluation of Biodistribution and Safety of Adenovirus Vectors Containing Group B Fibers After Intravenous Injection into Baboons
Human Gene Therapy·2005· 103 citedOpen Access
Interference with the IL-1-Signaling Pathway Improves the Toxicity Profile of Systemically Applied Adenovirus Vectors
The Journal of Immunology·2005· 50 citedOpen Access
Adenovirus Binding to Blood Factors Results in Liver Cell Infection and Hepatotoxicity
Journal of Virology·2005· 423 citedOpen Access
Development and Assessment of Human Adenovirus Type 11 as a Gene Transfer Vector
Journal of Virology·2005· 102 citedOpen Access
Deletion of Penton RGD Motifs Affects the Efficiency of both the Internalization and the Endosome Escape of Viral Particles Containing Adenovirus Serotype 5 or 35 Fiber Knobs
Journal of Virology·2004· 126 citedOpen Access
Genome Size and Structure Determine Efficiency of Postinternalization Steps and Gene Transfer of Capsid-Modified Adenovirus Vectors in a Cell-Type-Specific Manner
Journal of Virology·2004· 37 citedOpen Access
Analysis of Adenovirus Sequestration in the Liver, Transduction of Hepatic Cells, and Innate Toxicity after Injection of Fiber-Modified Vectors
Journal of Virology·2004· 205 citedOpen Access
Xenograft Models for Liver Metastasis: Relationship between Tumor Morphology and Adenovirus Vector Transduction
Molecular Therapy·2004· 39 citedOpen Access
The effect of sequestration by nontarget tissues on anti-tumor efficacy of systemically applied, conditionally replicating adenovirus vectors
Molecular Therapy·2003· 60 citedOpen Access
Insulation from viral transcriptional regulatory elements enables improvement to hepatoma-specific gene expression from adenovirus vectors
Biochemical and Biophysical Research Communications·2003· 30 cited
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Frequent Co-authors

André Lieber(23), Shaoheng Ni(11), Dmitry M. Shayakhmetov(9), Robert Strauss(5), Anuj Gaggar(5), Daniel Stone(5), Sebastian Tuve(4), Steve R. Roffler(4), Akseli Hemminki(3), Ying Liu(3), Hongjie Wang(3), Roma Yumul(3), Ying Liu(2), Jonas Persson(2), Ines Beyer(2), Pascal Fender(2), Vladimir V. Ternovoi(2), Helen Gharwan(2), Kathrin M. Bernt(2), Hans‐Peter Kiem(2)