Kathrin M. Bernt

Children's Hospital of Philadelphia — United States

Medicine · Health Sciences

31h-index5.8kcitations164works5.42yr avg
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Research Topics

Acute Myeloid Leukemia Research(69), Acute Lymphoblastic Leukemia research(33), Epigenetics and DNA Methylation(31), Protein Degradation and Inhibitors(30), CAR-T cell therapy research(20)

Publications164 total

CCR4 expression defines a targetable subset of T-cell acute lymphoblastic leukemia
Blood Advances·2026Open Access
CD19 CAR T-cell Therapy in Infant B-ALL: Durable Remissions, Relapse Patterns, and Molecular Correlates
Transplantation and Cellular Therapy·2026
CRISPR-based functional genomics for dissecting therapeutic dependency in primary acute myeloid leukemia samples
Molecular Cell·2026Open Access
Molecular Plasticity Results in Oncofetal Reprogramming and Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia
Blood Cancer Discovery·2025
Combinatorial inhibition of LSD1 and Menin induces therapeutic differentiation in AML
2025Open Access
Chemotherapy selects for myeloid subclones in multiple subtypes of B-cell acute lymphoblastic leukemia
Blood·2025
Genome-wide association study of childhood B-cell acute lymphoblastic leukemia reveals novel African ancestry-specific susceptibility loci
Nature Communications·2025· 1 citedOpen Access
Upfront menin-inhibitor resistance in multiply pretreated leukemias
Experimental Hematology·2025· 2 citedOpen Access
AML Care at Home: An Evidence-Based Toolkit to Personalize the Care Setting for Recovery From Pediatric AML Chemotherapy
JCO Oncology Practice·2025
Editor’s Note: Small-Molecule Inhibition of the Acyl-Lysine Reader ENL as a Strategy against Acute Myeloid Leukemia
Cancer Discovery·2025Open Access
Longitudinal single-cell multiomic atlas of high-risk neuroblastoma reveals chemotherapy-induced tumor microenvironment rewiring
Nature Genetics·2025· 15 citedOpen Access
DYRK1A inhibition results in MYC and ERK activation rendering KMT2A-R acute lymphoblastic leukemia cells sensitive to BCL2 inhibition
Leukemia·2025· 2 citedOpen Access
Single-nucleus multiomic analysis of Beckwith-Wiedemann syndrome liver reveals PPARA signaling enrichment and metabolic dysfunction
Communications Biology·2025· 4 citedOpen Access
STAT1-mediated interferon signatures are associated with preclinical JAK inhibitor sensitivity in T-ALL
Blood·2025· 1 cited
Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcome
Blood·2025· 9 citedOpen Access
Integrated genomic analysis to reduce chromosomal analysis for the diagnosis of pediatric hematologic malignancies: addressing the shortage of cytogenetic technologists
Haematologica·2025· 1 citedOpen Access
GATA2 links stemness to chemotherapy resistance in acute myeloid leukemia
Blood·2025· 11 citedOpen Access
O53: Can integrated genomic analysis replace chromosomal analysis for the diagnosis of hematological malignancies: Addressing the shortage of cytogenetic technologists
Genetics in Medicine Open·2025Open Access
O11: Mutational spectra of >1000 pediatric acute leukemias and their clinical utility in prognosis, risk stratification, and precision medicine therapeutics
Genetics in Medicine Open·2025Open Access
Supplementary Table S4 from Identification and Characterization of Chemotherapy-Resistant High-Risk Neuroblastoma Persister Cells
2024Open Access
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Frequent Co-authors

Scott A. Armstrong(13), Fatemeh Alikarami‬(9), Simone S. Riedel(9), Kai Tan(8), Changya Chen(8), André Lieber(7), Tobias Neff(7), Amit Sinha(6), Nan Zhu(6), Stephen P. Hunger(6), Shaoheng Ni(6), Hongbo Xie(6), Jessica N. Haladyna(6), Scott R. Daigle(5), Roy M. Pollock(5), Alexandra Lenard(5), Taylor Yamauchi(5), Edward J. Olhava(4), Chia‐Hui Chen(4), David M. Barrett(4)