Anna‐Lena Ungell

Frölunda Specialist Hospital — Sweden

Medicine · Health Sciences

33h-index5.2kcitations74works7.02yr avg
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Research Topics

Drug Transport and Resistance Mechanisms(37), Pharmacological Effects and Toxicity Studies(19), Pharmacogenetics and Drug Metabolism(13), Drug Solubulity and Delivery Systems(11), Computational Drug Discovery Methods(7)

Publications74 total

Single‑Dose Pharmacokinetics and Safety of the Oral Galectin‑3 Inhibitor, Selvigaltin (GB1211), in Participants with Hepatic Impairment
Clinical Drug Investigation·2024· 7 cited
A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age‐dependent differences in absorption
Clinical and Translational Science·2022· 16 citedOpen Access
Intestinal Epithelium and Drug Transporters
2022· 1 cited
Review of paediatric gastrointestinal physiology relevant to the absorption of orally administered medicines
Advanced Drug Delivery Reviews·2021· 53 cited
Ontogeny of Small Intestinal Drug Transporters and Metabolizing Enzymes Based on Targeted Quantitative Proteomics
Drug Metabolism and Disposition·2021· 43 citedOpen Access
Impact of In Vitro Passive Permeability in a P-gp-transfected LLC-PK1 Model on the Prediction of the Rat and Human Unbound Brain-to-Plasma Concentration Ratio
Pharmaceutical Research·2020· 16 cited
(–)-N-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-N-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes
Drug Metabolism and Disposition·2020· 6 citedOpen Access
Application of Azamulin to Determine the Contribution of CYP3A4/5 to Drug Metabolic Clearance Using Human Hepatocytes
Drug Metabolism and Disposition·2020· 7 citedOpen Access
Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review
European Journal of Pharmaceutical Sciences·2020· 275 citedOpen Access
P71 - Prediction of P-GP mediated drug-drug interaction at the blood-brain barrier
Drug Metabolism and Pharmacokinetics·2020
P127 - Prediction of brain disposition in rat and human from in vitro data: Correction of passive permeation
Drug Metabolism and Pharmacokinetics·2020
Oral drug absorption in pediatrics: the intestinal wall, its developmental changes and current tools for predictions
Biopharmaceutics & Drug Disposition·2016· 93 citedOpen Access
Biopharmaceutical Support in Formulation Development
2016· 3 cited
Biopharmaceutical Support in Candidate Drug Selection
2016· 8 cited
Drug Transport Mechanisms Across the Intestinal Epithelium
2016· 1 cited
Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination
The AAPS Journal·2016· 57 citedOpen Access
Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical Models
Clinical Pharmacokinetics·2016· 97 citedOpen Access
Biopharmaceutical Support in Formulation Development
2013· 2 cited
Comprehensive study on regional human intestinal permeability and prediction of fraction absorbed of drugs using the Ussing chamber technique
European Journal of Pharmaceutical Sciences·2012· 216 cited
Characterization of THLE-Cytochrome P450 (P450) Cell Lines: Gene Expression Background and Relationship to P450-Enzyme Activity
Drug Metabolism and Disposition·2012· 19 cited
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Frequent Co-authors

Per Artursson(9), Hans Lennernäs(8), Anders Lindahl(7), Constanze Hilgendorf(6), Ismael Zamora(5), Åsa Sjöberg(4), Sheila Annie Peters(4), Johan Karlsson(3), Saskia N. de Wildt(3), Rose Hayeshi(3), Sibylle Neuhoff(3), Collen Masimirembwa(3), Jean‐Marie Nicolas(3), Johan Nicolaï(3), K.‐H. Graefe(3), Annick Seithel(2), Lars Knutson(2), Ulf Bredberg(2), Patrick Augustijns(2), Miriam G. Mooij(2)