Robert F. Rando

Medicine · Health Sciences

32h-index3.3kcitations92works0.02yr avg
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Research Topics

HIV/AIDS drug development and treatment(36), HIV Research and Treatment(35), Cytomegalovirus and herpesvirus research(18), DNA and Nucleic Acid Chemistry(12), Cervical Cancer and HPV Research(11)

Publications92 total

Cervicovaginal Safety of the Formulated, Biguanide‐Based Human Immunodeficiency Virus Type 1 (HIV‐1) Inhibitor NB325 in a Murine Model
BioMed Research International·2011· 4 citedOpen Access
Structure-activity relationships of polybiguanides with activity against human immunodeficiency virus type 1
Biomedicine & Pharmacotherapy·2010· 22 cited
Persistent Interactions between Biguanide-Based Compound NB325 and CXCR4 Result in Prolonged Inhibition of Human Immunodeficiency Virus Type 1 Infection
Antimicrobial Agents and Chemotherapy·2010· 18 citedOpen Access
A Styrene-<i>alt</i>-Maleic Acid Copolymer Is an Effective Inhibitor of R5 and X4 Human Immunodeficiency Virus Type 1 Infection
Journal of Biomedicine and Biotechnology·2010· 31 citedOpen Access
Immediate and Persistent Anti-HIV-1 Activity of the Biguanide-based Compound NB325 Involves Specific Interactions with the Viral Co-receptor CXCR4
Antiviral Research·2009· 1 cited
Specific Interactions between the Viral Coreceptor CXCR4 and the Biguanide-Based Compound NB325 Mediate Inhibition of Human Immunodeficiency Virus Type 1 Infection
Antimicrobial Agents and Chemotherapy·2008· 30 citedOpen Access
Critical Design Features of Phenyl Carboxylate-Containing Polymer Microbicides
Antimicrobial Agents and Chemotherapy·2006· 16 citedOpen Access
In Vitro Antiretroviral Activity and In Vitro Toxicity Profile of SPD754, a New Deoxycytidine Nucleoside Reverse Transcriptase Inhibitor for Treatment of Human Immunodeficiency Virus Infection
Antimicrobial Agents and Chemotherapy·2006· 43 citedOpen Access
Preclinical Evaluation of Anti-HIV-1 Polybiguanide Vaginal Microbicides in a Murine Model of Toxicity and Inflammation
Retrovirology·2005· 4 citedOpen Access
Improvement of Polybiguanide-based Microbicides Using Computational Design Methodologies
Retrovirology·2005Open Access
The Presence of Mucin Increases the Anti-HIV-1 Activity of the Candidate Microbicide Polyethylene Hexamethylene Biguanide (PEHMB)
Retrovirology·2005Open Access
hmm.Coreceptor Perturbation as a Possible Mechanism Underlying the Immediate and Persistent Anti-HIV-1 Activity of the Microbicidal Compound PEHMB
Retrovirology·2005Open Access
Use of the Synthetic Copolymer PSMA as a Component in a Combination Microbicide Active Against HIV-1
Retrovirology·2005· 3 citedOpen Access
Polybiguanides, particularly polyethylene hexamethylene biguanide, have activity against human immunodeficiency virus type 1
Biomedicine & Pharmacotherapy·2005· 92 cited
Mouse Model of Cervicovaginal Toxicity and Inflammation for Preclinical Evaluation of Topical Vaginal Microbicides
Antimicrobial Agents and Chemotherapy·2004· 87 citedOpen Access
Toward the Development of a Virus-Cell-Based Assay for the Discovery of Novel Compounds against Human Immunodeficiency Virus Type 1
Antimicrobial Agents and Chemotherapy·2003· 13 citedOpen Access
CHEMOSENSITIZATION OF BLADDER CARCINOMA CELLS BY BCL-xL ANTISENSE OLIGONUCLEOTIDES
The Journal of Urology·2001· 36 cited
ChemInform Abstract: Parallel Synthesis of Isatin‐Based Serine Protease Inhibitors.
ChemInform·2001
Selection of Resistance-Conferring Mutations in HIV-1 by the Nucleoside Reverse Transcriptase Inhibitors (+/-)dOTC and (+/-)dOTFC
Antiviral chemistry & chemotherapy·2000· 9 cited
Bcl-xL in prostate cancer cells: effects of overexpression and down-regulation on chemosensitivity.
PubMed·2000· 171 cited
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Frequent Co-authors

Joshua O. Ojwang(8), Michael E. Hogan(7), Jean Bédard(6), Fred C. Krebs(5), Mohamed E. Labib(5), Brian Wigdahl(5), Éva Gönczöl(4), Nghe Nguyen‐Ba(4), Terry L. Bowlin(4), John H. Huffman(4), Thomas V. Sedlacek(3), Paul A. Cossum(3), Naijie Jing(3), Erik De Clercq(3), Susan M. Fennewald(3), Stanley A. Plotkin(3), Suzanne May(3), John C. Drach(3), Shendra Passic(3), Steven R. Lindheim(2)