Yun-Zheng Le

Nanchang University — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index2.4kcitations91works1.22yr avg
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Research Topics

Retinal Development and Disorders(41), Retinal Diseases and Treatments(34), Glaucoma and retinal disorders(12), CRISPR and Genetic Engineering(8), Adenosine and Purinergic Signaling(6)

Publications89 total

ZO-1/Tjp1 and ZO-2/Tjp2 deletion in retinal pigment epithelium causes progressive retinal degeneration
iScience·2025Open Access
<scp>TRIM47</scp> Facilitates Osteosarcoma Progression via Destabilising <scp>FBP1</scp> and Thus Activation of Wnt/β‐Catenin Pathway
Journal of Cellular and Molecular Medicine·2025Open Access
Pan-cancer analysis of oncogenic role of MAGOH and experiment validation in hepatocellular carcinoma
Scientific Reports·2025Open Access
Brain-Derived Neurotrophic Factor in Retinal Integrity Under Diabetic and Hypoxic Conditions
Advances in experimental medicine and biology·2025
SPIN1 accelerates tumorigenesis and confers radioresistance in non-small cell lung cancer by orchestrating the FOXO3a/FOXM1 axis
Cell Death and Disease·2024· 6 citedOpen Access
Critical Role of VEGF as a Direct Regulator of Photoreceptor Function
Advances in experimental medicine and biology·2023· 2 cited
Dependence of Retinal Pigment Epithelium Integrity on the NRF2–Heme Oxygenase-1 Axis
Investigative Ophthalmology & Visual Science·2022· 4 citedOpen Access
VEGF as a Direct Functional Regulator of Photoreceptors and Contributing Factor to Diabetes-Induced Alteration of Photoreceptor Function
Biomolecules·2021· 10 citedOpen Access
VEGF Mediates Retinal Müller Cell Viability and Neuroprotection through BDNF in Diabetes
Biomolecules·2021· 36 citedOpen Access
GDNF and BDNF are positive regulators for Müller cell viability through similar but divergent mechanisms
Investigative Ophthalmology & Visual Science·2020Open Access
Mechanism of BDNF-mediated neuroprotection: critical role of Müller glia in diabetic retinopathy and age-related macular degeneration
Investigative Ophthalmology & Visual Science·2019Open Access
The Contribution of Endoplasmic Reticulum Calcium Deficiency to Mistrafficking of Cone Outer Segment Proteins in CNG Channel Deficiency
Investigative Ophthalmology & Visual Science·2019Open Access
The Role of Endoplasmic Reticulum (ER) Calcium Channels in ER Stress and Cone Death in CNG Channel Deficiency
Investigative Ophthalmology & Visual Science·2019Open Access
Ryanodine Receptor 2 Contributes to Impaired Protein Localization in Cyclic Nucleotide-Gated Channel Deficiency
eNeuro·2019· 11 citedOpen Access
Loss of X-box binding protein 1 in Müller cells augments retinal inflammation in a mouse model of diabetes
Diabetologia·2019· 47 citedOpen Access
Noninvasive Diagnosis of Regional Alteration of Retinal Morphology and Structure with Optical Coherence Tomography in Rodents
Advances in experimental medicine and biology·2019· 4 cited
Critical Role of Trophic Factors in Protecting Müller Glia: Implications to Neuroprotection in Age-Related Macular Degeneration, Diabetic Retinopathy, and Anti-VEGF Therapies
Advances in experimental medicine and biology·2019· 9 cited
Mechanisms of Müller glia-mediated neuroprotection in diabetic retinopathy and hypoxic retinal diseases
Investigative Ophthalmology & Visual Science·2018Open Access
VEGF as a Trophic Factor for Müller Glia in Hypoxic Retinal Diseases
Advances in experimental medicine and biology·2018· 10 cited
G protein-coupled receptor 91 signaling in diabetic retinopathy and hypoxic retinal diseases
Vision Research·2017· 27 citedOpen Access
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Frequent Co-authors

Meili Zhu(18), Lixin Zheng(5), John D. Ash(5), Robert E. Anderson(5), Huizhuo Xu(4), Brian Sauer(4), Shuhua Fu(4), Shuqian Dong(3), Yumi Ueki(3), Jianyan Hu(3), Qiang Wu(3), L. C. Vining(3), Xueliang Xu(2), Michael H. Elliott(2), Alfred S. Lewin(2), Chang‐Yun Wang(2), Zhiming Song(2), Martin‐Paul Agbaga(2), Joshua J. Wang(2), Chen Chen(2)