Alfred S. Lewin

University of Florida — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

54h-index10.8kcitations372works3.72yr avg
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Research Topics

Retinal Development and Disorders(133), Retinal Diseases and Treatments(52), Mitochondrial Function and Pathology(52), Virus-based gene therapy research(46), Photoreceptor and optogenetics research(40)

Publications372 total

Modulation of retinal inflammation delays degeneration in a mouse model of geographic atrophy
Scientific Reports·2025· 1 citedOpen Access
Mitochondrial DNA Damage in the Retinal Pigmented Epithelium (RPE) and Its Role in RPE Pathobiology
Advances in experimental medicine and biology·2025
Corneal application of SOCS1/3 peptides for the treatment of eye diseases mediated by inflammation and oxidative stress
Frontiers in Immunology·2024· 10 citedOpen Access
Buspirone Enhances Cell Survival and Preserves Structural Integrity during Oxidative Injury to the Retinal Pigment Epithelium
Antioxidants·2023· 9 citedOpen Access
Suppressor of Cytokine Signaling 3 Derived Peptide as a Therapeutic for Inflammatory, and Oxidative Stress Induced Damage to the Retina
2023· 5 citedOpen Access
Modulation of Retinal Inflammation Delays Degeneration in a Mouse Model of Geographic Atrophy
2023Open Access
Binocular benefit following monocular subretinal AAV injection in a mouse model of autosomal dominant retinitis pigmentosa (adRP)
Vision Research·2023· 7 citedOpen Access
Replication Data for Binocular benefit following monocular subretinal AAV injection in a mouse model of autosomal dominant retinitis pigmentosa
Harvard Dataverse·2023Open Access
Inhibition of Ryanodine Receptor 1 Reduces Endoplasmic Reticulum (ER) Stress and Promotes ER Protein Degradation in Cyclic Nucleotide-Gated Channel Deficiency
Advances in experimental medicine and biology·2023· 1 citedOpen Access
Amelioration of Leigh syndrome induced by mouse blastocyst complementation with a mutant human mitochondrial ATP synthase 6
Clinical and Translational Discovery·2022Open Access
Gene Therapy for Rhodopsin Mutations
Cold Spring Harbor Perspectives in Medicine·2022· 4 citedOpen Access
Individual and Synergistic Anti-Coronavirus Activities of SOCS1/3 Antagonist and Interferon α1 Peptides
Frontiers in Immunology·2022· 12 citedOpen Access
Gene Delivery of a Caspase Activation and Recruitment Domain Improves Retinal Pigment Epithelial Function and Modulates Inflammation in a Mouse Model with Features of Dry Age-Related Macular Degeneration
Journal of Ocular Pharmacology and Therapeutics·2022· 5 citedOpen Access
Amelioration of Leigh syndrome induced by mouse blastocyst complementation with a mutant human mitochondrial ATP synthase 6
Research Square (Research Square)·2021Open Access
Gene Therapy for Rhodopsin-associated Autosomal Dominant Retinitis Pigmentosa
International Ophthalmology Clinics·2021· 16 citedOpen Access
Binocular Benefit Following Monocular Subretinal AAV Injection in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa (adRP)
2021Open Access
Buspirone is protective against oxidative stress induced changes in cell culture and animal models of RPE oxidative injury
Investigative Ophthalmology & Visual Science·2021· 2 citedOpen Access
MODELING ACCELERATED RETINAL AGING USING A DOMINANT MUTANT OF THE DNA POLYMERASE GAMMA SUB-UNIT 1
Investigative Ophthalmology & Visual Science·2021Open Access
R9-SOCS1-KIR Peptide Abrogates Lipopolysaccharide Mediated Inflammation: Implications for the Treatment of Endotoxin Induced Uveitis
Investigative Ophthalmology & Visual Science·2021Open Access
Erythropoietin Gene Therapy Delays Retinal Degeneration Resulting from Oxidative Stress in the Retinal Pigment Epithelium
Antioxidants·2021· 19 citedOpen Access
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Frequent Co-authors

William W. Hauswirth(30), Xiaoping Qi(10), John Guy(10), Sanford L. Boye(10), Vince A. Chiodo(6), Marina S. Gorbatyuk(6), Nicholas Muzyczka(5), Haoyu Mao(4), Ronald J. Mandel(4), William A. Beltran(4), Layla F Sullivan(4), Rajeshwari D. Koilkonda(4), Vittorio Porciatti(4), Michael E. Boulton(3), Matthew M. LaVail(3), Qiuhong Li(3), Jijing Pang(3), Oleg S. Gorbatyuk(3), Wen‐Tao Deng(3), Artur V. Cideciyan(3)