P H Yuen

The University of Texas MD Anderson Cancer Center — United States

Immunology and Microbiology · Life Sciences

19h-index1.1kcitations39works0.02yr avg
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Research Topics

HIV Research and Treatment(21), Virus-based gene therapy research(12), interferon and immune responses(8), HIV/AIDS drug development and treatment(6), RNA Research and Splicing(4)

Publications39 total

A single Glu62-to-Lys62 mutation in the Mos residues of the R7Δ447Gag-tMos protein causes the mutant virus to induce brain lesions
Oncogene·2001· 2 cited
Studies on the pathology, especially brain hemorrhage and angioendotheliomas, induced by two new mos-containing viruses
Journal of NeuroVirology·2000· 4 cited
Studies on the pathology, especially brain lesions, induced by R7, a spontaneous mutant of Moloney murine sarcoma virus 124.
PubMed·1998· 2 cited
ts1 MoMuLV: A Murine Model of Neuroimmunodegeneration
1998· 10 cited
R7, a Spontaneous Mutant of Moloney Murine Sarcoma Virus 124 with Three Direct Repeats and an In-Frame Truncatedgag-mosGene, Induces Brain Lesions
Virology·1997· 4 cited
Establishment and characterization of conditionally immortalized astrocytes to study their interaction with ts1, a neuropathogenic mutant of Moloney murine leukemia virus
Journal of NeuroVirology·1997· 28 cited
Long-Term Cultivation and Productive Infection of Primary Thymocyte Cultures by a Thymocytopathic Murine Retrovirus
Virology·1996· 4 citedOpen Access
Cell types in the central nervous system infected by murine retroviruses: implications for the mechanisms of neurodegeneration.
PubMed·1994· 14 cited
Murine retrovirus-induced depletion of T cells is mediated through activation-induced death by apoptosis
Journal of Virology·1994· 33 citedOpen Access
Protein C deficiency Hong Kong 1 and 2: hereditary protein C deficiency caused by two mutant alleles, a 5-nucleotide deletion and a missense mutation
Blood·1992· 3 citedOpen Access
Protein C deficiency Hong Kong 1 and 2: hereditary protein C deficiency caused by two mutant alleles, a 5-nucleotide deletion and a missense mutation
Blood·1992· 18 citedOpen Access
Characterization of a continuous lymphocyte cell line derived from BALB/c mice inoculated with a recombinant Moloney murine leukemia virus-TB.
PubMed·1992
Molecular Basis of Neurologic Disorders Induced by a Mutant, ts1, of Moloney Murine Leukemia Virus
Humana Press eBooks·1992· 25 cited
SV7, a molecular clone of Moloney murine sarcoma virus 349, transforms vascular endothelial cells.
PubMed·1991· 9 citedOpen Access
Construction and characterization of expression systems for the env gene of ts1, a mutant of Moloney murine leukemia virus-TB
Virus Research·1991· 11 cited
Site-directed mutagenesis of the codon for Ile-25 in gPr80env alters the neurovirulence of ts1, a mutant of Moloney murine leukemia virus TB
Journal of Virology·1990· 34 citedOpen Access
Moloney murine sarcoma virus 349 induces Kaposi's sarcomalike lesions in Balb/c mice.
PubMed·1990· 17 cited
A Val-25-to-Ile substitution in the envelope precursor polyprotein, gPr80env, is responsible for the temperature sensitivity, inefficient processing of gPr80env, and neurovirulence of ts1, a mutant of Moloney murine leukemia virus TB
Journal of Virology·1990· 86 citedOpen Access
ts1, A mutant of moloney murine leukemia virus-TB, causes both immunodeficiency and neurologic disorders in BALB/c Mice
Virology·1989· 50 cited
The reduced virulence of the thymotropic Moloney murine leukemia virus derivative MoMuLV-TB is mapped to 11 mutations within the U3 region of the long terminal repeat
Journal of Virology·1989· 34 citedOpen Access
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Frequent Co-authors

P.K.Y. Wong(28), M.M. Soong(7), Paul F. Szurek(4), Carlo Knupp(3), Roderick MacLeod(2), G. Prasad(2), David E Malehorn(2), S. J. Kaufman(2), Yusuke Sugahara(2), Osamu Miura(2), N Aoki(2), M.S. Kissil(2), William S. Lynn(2), Yiyun Lin(2), E A Ryan(2), Yeonsoo Kwak(2), Hollie J. Westly(1), Alice J. Kleiss(1), Keith W. Kelley(1), R Jerzy(1)