Ennio Ongini

Tethys Research Institute — Italy

Biochemistry, Genetics and Molecular Biology · Life Sciences

52h-index8.1kcitations152works0.02yr avg
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Research Topics

Adenosine and Purinergic Signaling(52), Receptor Mechanisms and Signaling(40), Pharmacological Receptor Mechanisms and Effects(22), Neuroscience and Neuropharmacology Research(17), Nitric Oxide and Endothelin Effects(17)

Publications152 total

Repeated dosing of NCX 667, a new nitric oxide (NO) donor, retains IOP-lowering activity in animal models of glaucoma
2017· 3 cited
IOP-lowering effects of NCX 667 in combination with travoprost in ocular normotensive and transient hypertensive rabbits
2016· 2 cited
Intraocular pressure-lowering and ocular exposure of NCX 1653, a novel nitric oxide-donating travoprost in models of ocular hypertension and glaucoma
2016
Intraocular Pressure–Lowering Activity of NCX 470, a Novel Nitric Oxide–Donating Bimatoprost in Preclinical Models
Investigative Ophthalmology & Visual Science·2015· 37 citedOpen Access
Naproxcinod shows significant advantages over naproxen in the mdx model of Duchenne Muscular Dystrophy
Orphanet Journal of Rare Diseases·2015· 15 citedOpen Access
NCX 667, a novel nitric oxide (NO) donor lowers intraocular pressure (IOP) in ocular normotensive and hypertensive eyes of rabbits and non-human primates
2015
NCX 470, a nitric oxide (NO)-donating bimatoprost lowers intraocular pressure in rabbits, dogs and non-human primate models of glaucoma
2015
Nitric Oxide (NO): An Emerging Target for the Treatment of Glaucoma
Investigative Ophthalmology & Visual Science·2014· 197 citedOpen Access
Intraocular pressure and cGMP aqueous humor levels in spontaneous ocular hypertensive rabbits and following transient IOP changes
2013
Nitric Oxide-Donating Atorvastatin Attenuates Neutrophil Recruitment During Vascular Inflammation Independent of Changes in Plasma Cholesterol
Cardiovascular Drugs and Therapy·2013· 11 cited
Treatment with a Nitric Oxide-Donating NSAID Alleviates Functional Muscle Ischemia in the Mouse Model of Duchenne Muscular Dystrophy
PLoS ONE·2012· 35 citedOpen Access
Nitric oxide prevents atorvastatin‐induced skeletal muscle dysfunction and alterations in mice
Muscle & Nerve·2012· 12 cited
Gastrointestinal-Sparing Effects of Novel NSAIDs in Rats with Compromised Mucosal Defence
PLoS ONE·2012· 93 citedOpen Access
Treatment with a nitric oxide‐donating NSAID counteracts functional muscle ischemia in dystrophin‐deficient mdx mice
The FASEB Journal·2012· 1 cited
Nitric oxide enhances the anti-inflammatory and anti-atherogenic activity of atorvastatin in a mouse model of accelerated atherosclerosis
Cardiovascular Research·2012· 51 citedOpen Access
The nitric oxide donating triamcinolone acetonide NCX 434 does not increase intraocular pressure and reduces endothelin-1 induced biochemical and functional changes in the rabbit eye
British Journal of Ophthalmology·2012· 8 cited
Proton Pump Inhibitors Exacerbate NSAID-Induced Small Intestinal Injury by Inducing Dysbiosis
Gastroenterology·2011· 452 citedOpen Access
Proton Pump Inhibitors and Low-Dose Aspirin Markedly Exacerbate NSAID-Induced Small Intestinal Injury: A Link to Dysbiosis?
Gastroenterology·2011· 9 cited
The Nitric Oxide (no)-donating Triamcinolone Acetonide, NCX 434, Does Not Increase Intraocular Pressure and Reduces Endothelin-1-induced Biochemical and Functional Changes In The Rabbit Eye
2011
Enhanced Oxygen Saturation in Optic Nerve Head of Non-Human Primate Eyes Following the Intravitreal Injection of NCX 434, an Innovative Nitric Oxide-Donating Glucocorticoid
Journal of Ocular Pharmacology and Therapeutics·2011· 24 citedOpen Access
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Frequent Co-authors

Angela Monopoli(13), Silvio Dionisotti(8), Francesco Impagnatiello(7), Laura Gasparini(6), Pier Giovanni Baraldi(6), Rosalia Bertorelli(6), Pier Andrea Borea(5), Cristina Zocchi(5), Barbara Cacciari(4), Giampiero Spalluto(4), Luiz Belardinelli(4), Katia Varani(4), Bertil B. Fredholm(3), Gianluca Lozza(3), Piero Del Soldato(3), Marina Rossato Adami(3), Massimiliano Guzzetta(3), Luca Raiteri(3), Andrea Bonfanti(3), Maurizio Raiteri(3)