Christopher M. DaCosta

Lexicon Pharmaceuticals (United States) — United States

Medicine · Health Sciences

12h-index732citations16works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Pancreatic function and diabetes(6), Diabetes Treatment and Management(5), Adipose Tissue and Metabolism(4), Growth Hormone and Insulin-like Growth Factors(2), Metabolism, Diabetes, and Cancer(2)

Publications16 total

Mice Lacking Gpr75 are Hypophagic and Thin
Dove Medical Press (Taylor and Francis Group)·2022· 19 citedOpen Access
High-Throughput Screening of Mouse Gene Knockouts Identifies Established and Novel High Body Fat Phenotypes
Diabetes Metabolic Syndrome and Obesity·2021· 14 citedOpen Access
Progressive Degenerative Myopathy and Myosteatosis in ASNSD1-Deficient Mice
Veterinary Pathology·2020· 10 citedOpen Access
<p>Obesity of G2e3 Knockout Mice Suggests That Obesity-Associated Variants Near Human G2E3 Decrease G2E3 Activity</p>
Diabetes Metabolic Syndrome and Obesity·2020· 22 citedOpen Access
LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice
Journal of Pharmacology and Experimental Therapeutics·2017· 34 citedOpen Access
Nephronophthisis and Retinal Degeneration in <i>Tmem218<sup>–/–</sup></i> Mice
Veterinary Pathology·2014· 16 cited
Effect of LX4211 on Glucose Homeostasis and Body Composition in Preclinical Models
Journal of Pharmacology and Experimental Therapeutics·2014· 50 cited
LX4211 Increases Serum Glucagon-Like Peptide 1 and Peptide YY Levels by Reducing Sodium/Glucose Cotransporter 1 (SGLT1)–Mediated Absorption of Intestinal Glucose
Journal of Pharmacology and Experimental Therapeutics·2013· 181 cited
Improved glycemic control in mice lacking Sglt1 and Sglt2
American Journal of Physiology-Endocrinology and Metabolism·2012· 157 cited
Pathology of Congenital Generalized Lipodystrophy in <i>Agpat2<sup>–/–</sup></i> Mice
Veterinary Pathology·2010· 29 citedOpen Access
Requirement for Class II Phosphoinositide 3-Kinase C2α in Maintenance of Glomerular Structure and Function
Molecular and Cellular Biology·2010· 59 citedOpen Access
Novel <scp>l</scp>-Xylose Derivatives as Selective Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitors for the Treatment of Type 2 Diabetes
Journal of Medicinal Chemistry·2009· 76 citedOpen Access
High‐throughput Screening of Mouse Knockout Lines Identifies True Lean and Obese Phenotypes
Obesity·2008· 61 cited
Collagen promoter-GFP transgenic mice provide a model to study collagen gene expression during experimental intestinal inflammation and injury in vivo and in vitro
Gastroenterology·2001
Evidence for inhibition of cytokine action by growth hormone during recovery from experimental enterocolitis
Regulatory Peptides·2000
Enhanced survival and mucosal repair following DSS colitis in transgenic mice that overexpress bovine growth hormone
Gastroenterology·2000· 4 cited

Frequent Co-authors

Melanie K. Shadoan(9), Zhi‐Ming Ding(8), Gwenn M. Hansen(7), D.R. Powell(7), Brian Zambrowicz(6), Deon Doree(6), Peter Vogel(6), Robert Brommage(6), David R. Powell(5), Faika Mseeh(5), Lindsey Buhring(5), Kenneth A. Platt(5), Melinda Smith(4), Arthur Sands(4), Jean‐Pierre Revelli(4), Jennifer Greer(3), Angela L. Harris(3), Alan Wilson(3), Robert W. Read(3), Kristen L. Williams(3)