Kenneth A. Platt

Lexicon Pharmaceuticals (United States) — United States

Medicine · Health Sciences

29h-index6.2kcitations44works0.52yr avg
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Research Topics

Pancreatic function and diabetes(7), Developmental Biology and Gene Regulation(5), Diabetes Treatment and Management(5), Metabolism, Diabetes, and Cancer(5), Hedgehog Signaling Pathway Studies(4)

Publications44 total

Acyl-CoA Synthetase 5 Knockout and Inhibitors Protect Against Diet-Induced Obesity in Mice by Activating the Ileal Brake
Journal of the Endocrine Society·2025Open Access
Mice Lacking <i>Mrs2 Magnesium Transporter</i> are Hypophagic and Thin When Maintained on a High-Fat Diet
Endocrinology·2024· 1 cited
Mice Lacking Gpr75 are Hypophagic and Thin
Dove Medical Press (Taylor and Francis Group)·2022· 19 citedOpen Access
High-Throughput Screening of Mouse Gene Knockouts Identifies Established and Novel High Body Fat Phenotypes
Diabetes Metabolic Syndrome and Obesity·2021· 14 citedOpen Access
&lt;p&gt;Obesity of G2e3 Knockout Mice Suggests That Obesity-Associated Variants Near Human G2E3 Decrease G2E3 Activity&lt;/p&gt;
Diabetes Metabolic Syndrome and Obesity·2020· 22 citedOpen Access
Combined Deletion of Slc30a7 and Slc30a8 Unmasks a Critical Role for ZnT8 in Glucose-Stimulated Insulin Secretion
Endocrinology·2016· 36 citedOpen Access
Fatty acid desaturase 1 knockout mice are lean with improved glycemic control and decreased development of atheromatous plaque
Diabetes Metabolic Syndrome and Obesity·2016· 40 citedOpen Access
Correction: Corrigendum: Adiponectin receptor 1 conserves docosahexaenoic acid and promotes photoreceptor cell survival
Nature Communications·2015· 3 citedOpen Access
Adiponectin receptor 1 conserves docosahexaenoic acid and promotes photoreceptor cell survival
Nature Communications·2015· 122 citedOpen Access
Genetic Deletion of Mst1 Alters T Cell Function and Protects against Autoimmunity
PLoS ONE·2014· 47 citedOpen Access
Malformation of Incisor Teeth in <i>Grem2<sup>-/-</sup></i> Mice
Veterinary Pathology·2014· 28 cited
Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia
American Journal of Physiology-Renal Physiology·2013· 296 citedOpen Access
Inhibition of HDAC2 Protects the Retina From Ischemic Injury
Investigative Ophthalmology & Visual Science·2013· 45 citedOpen Access
Improved glycemic control in mice lacking Sglt1 and Sglt2
American Journal of Physiology-Endocrinology and Metabolism·2012· 157 cited
Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus
American Journal of Physiology-Renal Physiology·2012· 365 citedOpen Access
Characterization of PTPRG in Knockdown and Phosphatase-Inactive Mutant Mice and Substrate Trapping Analysis of PTPRG in Mammalian Cells
PLoS ONE·2012· 10 citedOpen Access
Profound Obesity Secondary to Hyperphagia in Mice Lacking Kinase Suppressor of Ras 2
Obesity·2010· 54 cited
SGLT2 Mediates Glucose Reabsorption in the Early Proximal Tubule
Journal of the American Society of Nephrology·2010· 544 citedOpen Access
A mouse knockout library for secreted and transmembrane proteins
Nature Biotechnology·2010· 333 cited
SGLT2 mediates glucose reabsorption in the early proximal tubule
The FASEB Journal·2010· 4 cited
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Frequent Co-authors

Brian Zambrowicz(11), Peter Vogel(9), D.R. Powell(9), Gwenn M. Hansen(7), Arthur Sands(7), Robert Brommage(7), Isaac Van Sligtenhorst(6), Melanie K. Shadoan(6), Jean‐Pierre Revelli(6), Dennis S. Rice(5), Urvi Desai(5), Christopher M. DaCosta(5), Zhi‐Ming Ding(5), Deon Doree(5), Volker Vallon(4), Scott C. Thomson(4), Timo Rieg(4), Kathleen H. Holt(4), Laura Kirkpatrick(4), Alexandra L. Joyner(3)