Jerome H. Fleisch

Eli Lilly (United States) — United States

Medicine · Health Sciences

19h-index1.5kcitations55works0.02yr avg
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Research Topics

Asthma and respiratory diseases(17), Receptor Mechanisms and Signaling(11), Inhalation and Respiratory Drug Delivery(7), Respiratory and Cough-Related Research(7), Nitric Oxide and Endothelin Effects(6)

Publications55 total

LY393615, a novel neuronal Ca2+ and Na+ channel blocker with neuroprotective effects in models of in vitro and in vivo cerebral ischemia
Brain Research·2001· 15 cited
Effects of the second-generation leukotriene B4 receptor antagonist, LY293111Na, on leukocyte infiltration and collagen-induced arthritis in mice
European Journal of Pharmacology·2000· 38 cited
ARL 17477, a selective nitric oxide synthase inhibitor, with neuroprotective effects in animal models of global and focal cerebral ischaemia
Brain Research·2000· 50 cited
Pharmacology of LY315920/S-5920, [[3-(Aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1 H-indol-4-yl]oxy]acetate, a Potent and Selective Secretory Phospholipase A2Inhibitor: A New Class of Anti-Inflammatory Drugs, SPI
Journal of Pharmacology and Experimental Therapeutics·1999· 88 cited
Pharmacologic Actions of the Second-Generation Leukotriene B4 Receptor Antagonist LY293111: In Vitro Studies
Journal of Pharmacology and Experimental Therapeutics·1999· 58 cited
Quinoline-substituted dihydroindoles as cysLT1 (LTD4 receptor) antagonists
Bioorganic & Medicinal Chemistry Letters·1996· 8 cited
Development of novel anti-inflammatory agents: A pharmacologic perspective on leukotrienes and their receptors
Birkhäuser Basel eBooks·1996· 2 cited
Progress in Drug Research/Fortschritte der Arzneimittelforschung/Progrès des recherches pharmaceutiques
Birkhäuser Basel eBooks·1996
2-alkyl-4-ethyl-5-[6-methyl-6-(2H-tetrazol-5-yl)heptyloxy]phenol leukotriene B4 receptor antagonists
Bioorganic & Medicinal Chemistry Letters·1995· 7 cited
Differential Relaxant Responses of Guinea-pig Lung Strips and Bronchial Rings to Sodium Nitroprusside: A Mechanism Independent of cGMP Formation
Journal of Pharmacy and Pharmacology·1995· 15 cited
A novel leukotriene B4-receptor antagonist in endotoxin shock
Critical Care Medicine·1993· 47 cited
o-Phenylphenols: potent and orally active leukotriene B4 receptor antagonists
Journal of Medicinal Chemistry·1993· 8 citedOpen Access
Acid unit modifications of 1,2,4,5-substituted hydroxyacetophenones and the effect on in vitro and in vivo LTB4 receptor antagonism
Bioorganic & Medicinal Chemistry Letters·1993· 3 cited
Pulmonary actions of LY255283, a leukotriene B4 receptor antagonist
European Journal of Pharmacology·1992· 19 cited
Contributory role of lung pleura to release of anaphylactic mediators from guinea pig lung in response to ovalbumin or A23187
Biochemical Pharmacology·1992· 5 cited
Development of a series of phenyltetrazole leukotriene D4(LTD4) receptor antagonists
Journal of Medicinal Chemistry·1992· 16 cited
Optimization of the quinoline and substituted benzyl moieties of a series of phenyltetrazole leukotriene D4 receptor antagonists
Journal of Medicinal Chemistry·1992· 9 cited
Pharmacological and histological examinations of regional differences of guinea‐pig lung: a role of pleural surface smooth muscle in lung strip contraction
British Journal of Pharmacology·1992· 15 citedOpen Access
(Phenylmethoxy)phenyl derivatives of w-oxo- and w-tetrazolylalkanoic acids and related tetrazoles. Synthesis and evaluation as leukotriene D4 receptor antagonists
Journal of Medicinal Chemistry·1991· 13 cited
Leukotriene Receptor Antagonism and Augmentation of β-Receptor-mediated Events by LY171883
Journal of Pharmacy and Pharmacology·1990· 3 cited
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Frequent Co-authors

Lynn E. Rinkema(10), Carlos Romero(9), Stephen M. Spaethe(7), Klaus D. Haisch(5), Larry L. Froelich(5), Carlos R. Roman(5), Robert D. Dillard(4), Winston S. Marshall(4), Theodore Goodson(4), William T. Jackson(4), J. Scott Sawyer(4), Michael J. Sofia(4), David K. Herron(4), Sandra L. Cockerham(4), Nicholas J. Bach(3), Carol S. Hooker(3), David L. Saussy(3), Elwood Titus(3), F. Patrick Carr(3), Doris McCullough(3)