Tong-Shin Chang

Seoul National University — South Korea

Biochemistry, Genetics and Molecular Biology · Life Sciences

19h-index3.1kcitations28works1.02yr avg
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Research Topics

Redox biology and oxidative stress(12), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(7), Sulfur Compounds in Biology(5), Heat shock proteins research(4), Genomics, phytochemicals, and oxidative stress(3)

Publications28 total

NADPH oxidase 2 inhibitor GSK2795039 exerts antiplatelet and antithrombotic activity
Scientific Reports·2025· 1 citedOpen Access
Steric influence of 4′-position substituents and C2-Hexynyl group on A3AR antagonism in truncated 4′-Thioadenosine derivatives
Bioorganic Chemistry·2025· 1 cited
Identification of 6′-β-fluoro-homoaristeromycin as a potent inhibitor of chikungunya virus replication
European Journal of Medicinal Chemistry·2019· 18 citedOpen Access
Abstract 5853: Peroxiredoxin I-targeted AMRI-59 has a role of radiosensitizer by promoting induction of ROS/γH2AX/caspase pathway and suppression of ERK
Cancer Research·2017
Identification of cytoprotective constituents of the flower buds of Tussilago farfara against glucose oxidase-induced oxidative stress in mouse fibroblast NIH3T3 cells and human keratinocyte HaCaT cells
Archives of Pharmacal Research·2016· 25 cited
Sulfiredoxin inhibitor induces preferential death of cancer cells through reactive oxygen species-mediated mitochondrial damage
Free Radical Biology and Medicine·2015· 51 cited
A concise synthesis of tubuphenylalanine and epi-tubuphenylalanine via a diastereoselective Mukaiyama aldol reaction of silyl ketene acetal
Organic & Biomolecular Chemistry·2015· 6 cited
Effective Killing of Cancer Cells Through ROS-Mediated Mechanisms by AMRI-59 Targeting Peroxiredoxin I
Antioxidants and Redox Signaling·2015· 37 cited
Resveratrol inhibits collagen-induced platelet stimulation through suppressing NADPH oxidase and oxidative inactivation of SH2 domain-containing protein tyrosine phosphatase-2
Free Radical Biology and Medicine·2015· 33 cited
Recent Advances in Anticancer Chemotherapeutics based upon Azepine Scaffold
Anti-Cancer Agents in Medicinal Chemistry·2015· 15 cited
Structure–Activity Relationships of Neplanocin A Analogues as <i>S</i>-Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities
Journal of Medicinal Chemistry·2015· 40 citedOpen Access
Kaempferol suppresses collagen-induced platelet activation by inhibiting NADPH oxidase and protecting SHP-2 from oxidative inactivation
Free Radical Biology and Medicine·2015· 58 cited
Methods for detection and measurement of hydrogen peroxide inside and outside of cells
Molecules and Cells·2010· 424 cited
Pretreatment with interferon-γ protects microglia from oxidative stress via up-regulation of Mn-SOD
Free Radical Biology and Medicine·2009· 27 cited
Sulfiredoxin Translocation into Mitochondria Plays a Crucial Role in Reducing Hyperoxidized Peroxiredoxin III
Journal of Biological Chemistry·2009· 124 citedOpen Access
Mitochondrial reactive oxygen species originating from Romo1 exert an important role in normal cell cycle progression by regulating p27<sup>Kip1</sup>expression
Free Radical Research·2009· 49 citedOpen Access
Notch interferes with the scaffold function of JNK-interacting protein 1 to inhibit the JNK signaling pathway
Proceedings of the National Academy of Sciences·2005· 73 citedOpen Access
Controlled Elimination of Intracellular H <sub>2</sub> O2: Regulation of Peroxiredoxin, Catalase, and Glutathione Peroxidase via Post-translational Modification
Antioxidants and Redox Signaling·2005· 367 cited
Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxins
Current Opinion in Cell Biology·2005· 704 cited
Hydrogen Peroxide As Intracellular Messenger
Humana Press eBooks·2005· 4 cited
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Frequent Co-authors

Sue Goo Rhee(9), Woojin Jeong(7), Sang Won Kang(5), Jin Young Baek(5), Ji Yong Jang(4), Hyun Ae Woo(3), Eui‐Ju Choi(3), Su Bin Wang(3), Jae‐Sang Ryu(3), Sang Kook Lee(3), Lak Shin Jeong(3), Kap-Seok Yang(2), Sue Goo Rhee(2), Ssang‐Goo Cho(2), Hee-Sae Park(2), Myeong‐Jin Kim(2), Yun Soo Bae(2), Seung-Rock Lee(2), You Hyun Noh(2), Jin Woo Kim(2)