Mackenzie Welch

Biogen (United States) — United States

Medicine · Health Sciences

7h-index517citations12works0.02yr avg
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Research Topics

Parkinson's Disease Mechanisms and Treatments(6), Nuclear Receptors and Signaling(3), T-cell and B-cell Immunology(2), Alzheimer's disease research and treatments(2), Advanced Fluorescence Microscopy Techniques(2)

Publications12 total

Processing of progranulin into granulins involves multiple lysosomal proteases and is affected in frontotemporal lobar degeneration
Molecular Neurodegeneration·2021· 51 citedOpen Access
Genetically Encoded, pH-Sensitive mTFP1 Biosensor for Probing Lysosomal pH
ACS Sensors·2021· 84 citedOpen Access
α-Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson’s disease
JCI Insight·2021· 127 citedOpen Access
Processing of progranulin into granulins involves multiple lysosomal proteases and is affected in frontotemporal lobar degeneration
Research Square (Research Square)·2020Open Access
A genetically encoded, pH-sensitive mTFP1 biosensor for probing lysosomal pH
2020· 4 citedOpen Access
Alpha-synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson’s disease
2019· 10 citedOpen Access
Randomized phase I clinical trial of anti–α‐synuclein antibody BIIB054
Movement Disorders·2019· 187 citedOpen Access
Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose Study of Anti-Alpha-Synuclein Antibody BIIB054 in Patients with Parkinson’s Disease (S26.001)
Neurology·2018· 17 cited
High Reproducibility of ELISPOT Counts from Nine Different Laboratories
Cells·2015· 29 citedOpen Access
Log-Normal ELISPOT spot size distribution permits count harmonization among different laboratories
Journal for ImmunoTherapy of Cancer·2014· 2 citedOpen Access
Adapting dried blood spot sampling for an anti-therapeutic antibody immunogenicity assay
Journal of Immunological Methods·2013· 2 cited
Regulatory Issues for Evaluation of Therapies to Prevent or Arrest Disease Progression
Annals of Periodontology·1997· 4 cited

Frequent Co-authors

Danielle Graham(4), Andreas Weihofen(4), Anand Patwardhan(4), Aimee W. Kao(4), Mirosław Bryś(2), Laura Fanning(2), Aaron Ellenbogen(2), Minhua Yang(2), E. Koenig(2), Eric David(2), Tara Fox(2), Shavy Makh(2), Jason Aldred(2), Ira Goodman(2), Jesse M. Cedarbaum(2), Tracy Cole(2), Hien Zhao(2), Timothy J. Collier(2), Ivette M. Sandoval(2), Caryl E. Sortwell(2)